Display Settings:

Format

Send to:

Choose Destination

MYCNOS MYCN opposite strand [ Homo sapiens (human) ]

Gene ID: 10408, updated on 25-Jun-2015
Official Symbol
MYCNOSprovided by HGNC
Official Full Name
MYCN opposite strandprovided by HGNC
Primary source
HGNC:HGNC:16911
See related
Ensembl:ENSG00000233718; MIM:605374
Gene type
ncRNA
RefSeq status
VALIDATED
Organism
Homo sapiens
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo
Also known as
NCYM; NYCM; N-CYM; MYCN-AS1
Summary
This gene is located on the opposite strand of v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog (GeneID 4613). Transcription of this antisense gene may influence the progression of neuroblastoma by inhibiting transcription of v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog. This gene is represented as non-coding pending further experimental evidence of a protein product. Alternatively spliced transcript variants have been described. [provided by RefSeq, Jan 2014]
Orthologs
See MYCNOS in Epigenomics, MapViewer
Location:
2p24.1
Exon count:
5
Annotation release Status Assembly Chr Location
107 current GRCh38.p2 (GCF_000001405.28) 2 NC_000002.12 (15936265..15941723, complement)
105 previous assembly GRCh37.p13 (GCF_000001405.25) 2 NC_000002.11 (16076387..16081845, complement)

Chromosome 2 - NC_000002.12Genomic Context describing neighboring genes Neighboring gene ribosomal protein, large, P1 pseudogene 5 Neighboring gene MYCN upstream transcript (non-protein coding) Neighboring gene v-myc avian myelocytomatosis viral oncogene neuroblastoma derived homolog Neighboring gene gastric cancer associated transcript 3 (non-protein coding) Neighboring gene uncharacterized LOC105373443

GeneRIFs: Gene References Into FunctionsWhat's a GeneRIF?

Markers

Homology

Other Names

  • MYCN antisense RNA 1
  • MYCN opposite strand/antisense RNA (non-protein coding)
  • v-myc myelocytomatosis viral related oncogene, neuroblastoma derived opposite strand

Gene Ontology Provided by GOA

Function Evidence Code Pubs
protein binding IPI
Inferred from Physical Interaction
more info
PubMed 
Process Evidence Code Pubs
multicellular organismal development TAS
Traceable Author Statement
more info
PubMed 
negative regulation of apoptotic process IMP
Inferred from Mutant Phenotype
more info
PubMed 
negative regulation of kinase activity IDA
Inferred from Direct Assay
more info
PubMed 
positive regulation of cell proliferation IMP
Inferred from Mutant Phenotype
more info
PubMed 
regulation of protein stability IMP
Inferred from Mutant Phenotype
more info
PubMed 
Component Evidence Code Pubs
cytoplasm IDA
Inferred from Direct Assay
more info
PubMed 
nucleus IDA
Inferred from Direct Assay
more info
PubMed 

RefSeqs maintained independently of Annotated Genomes

These reference sequences exist independently of genome builds. Explain

These reference sequences are curated independently of the genome annotation cycle, so their versions may not match the RefSeq versions in the current genome build. Identify version mismatches by comparing the version of the RefSeq in this section to the one reported in Genomic regions, transcripts, and products above.

RNA

  1. NR_026766.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (2) lacks one exon and includes two alternate exons compared to variant 1.
    Source sequence(s)
    AC010145, S49953
    Related
    ENST00000419083
  2. NR_110230.1 RNA Sequence

    Status: VALIDATED

    Description
    Transcript Variant: This variant (1) represents the longer transcript.
    Source sequence(s)
    AC010145, BC002892
    Related
    ENST00000420452

RefSeqs of Annotated Genomes: Homo sapiens Annotation Release 107

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference GRCh38.p2 Primary Assembly

Genomic

  1. NC_000002.12 Reference GRCh38.p2 Primary Assembly

    Range
    15936265..15941723
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Alternate CHM1_1.1

Genomic

  1. NC_018913.2 Alternate CHM1_1.1

    Range
    16006172..16011631
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

Suppressed Reference Sequence(s)

The following Reference Sequences have been suppressed. Explain

  1. NM_006316.1: Suppressed sequence

    Description
    NM_006316.1: This RefSeq was permanently suppressed because currently there is support for the transcript but not for the protein.