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C3 complement C3 [ Pygoscelis adeliae (Adelie penguin) ]

Gene ID: 103916897, updated on 11-Mar-2024

Summary

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Gene symbol
C3
Gene description
complement C3
Locus tag
AS28_00908
Gene type
protein coding
RefSeq status
MODEL
Organism
Pygoscelis adeliae
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae; Pygoscelis
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
41
Annotation release Status Assembly Chr Location
100 current ASM69910v1 (GCF_000699105.1) Unplaced Scaffold NW_008824799.1 (8685..28212)

NW_008824799.1Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_008824799.1 Unplaced Scaffold Reference ASM69910v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables endopeptidase inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in complement activation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
LOW QUALITY PROTEIN: complement C3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Pygoscelis adeliae Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM69910v1 Primary Assembly

Genomic

  1. NW_008824799.1 Reference ASM69910v1 Primary Assembly

    Range
    8685..28212
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009323963.1 → XP_009322238.1  LOW QUALITY PROTEIN: complement C3

    Conserved Domains (8) summary
    cd00017
    Location:708 → 775
    ANATO; Anaphylatoxin homologous domain; C3a, C4a and C5a anaphylatoxins are protein fragments generated enzymatically in serum during activation of complement molecules C3, C4, and C5. They induce smooth muscle contraction. These fragments are homologous to ...
    cd02896
    Location:1024 → 1307
    complement_C3_C4_C5; Proteins similar to C3, C4 and C5 of vertebrate complement. The vertebrate complement system, comprised of a large number of distinct plasma proteins, is an effector of both the acquired and innate immune systems. The point of convergence of the ...
    pfam00207
    Location:798 → 894
    A2M; Alpha-2-macroglobulin family
    pfam01835
    Location:163 → 257
    A2M_N; MG2 domain
    pfam07677
    Location:1423 → 1518
    A2M_recep; A-macroglobulin receptor
    pfam07678
    Location:1079 → 1307
    A2M_comp; A-macroglobulin complement component
    pfam07703
    Location:493 → 632
    A2M_N_2; Alpha-2-macroglobulin family N-terminal region
    cl02512
    Location:1538 → 1681
    NTR_like; NTR_like domain; a beta barrel with an oligosaccharide/oligonucleotide-binding fold found in netrins, complement proteins, tissue inhibitors of metalloproteases (TIMP), and procollagen C-proteinase enhancers (PCOLCE), amongst others. In netrins, the ...
Nucleotide Protein
Heading Accession and Version

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