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MTHFD2L methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like [ Aptenodytes forsteri (emperor penguin) ]

Gene ID: 103898942, updated on 11-Mar-2024

Summary

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Gene symbol
MTHFD2L
Gene description
methylenetetrahydrofolate dehydrogenase (NADP+ dependent) 2 like
Locus tag
AS27_10810
Gene type
protein coding
RefSeq status
MODEL
Organism
Aptenodytes forsteri
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Sphenisciformes; Spheniscidae; Aptenodytes
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
8
Annotation release Status Assembly Chr Location
101 current ASM69914v1 (GCF_000699145.1) Unplaced Scaffold NW_008795298.1 (1226131..1257104, complement)

NW_008795298.1Genomic Context describing neighboring genes Neighboring gene epiregulin Neighboring gene epithelial mitogen Neighboring gene C-X-C motif chemokine 5-like Neighboring gene interleukin-8

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_008795298.1 Unplaced Scaffold Reference ASM69914v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables methenyltetrahydrofolate cyclohydrolase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables methylenetetrahydrofolate dehydrogenase (NAD+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables methylenetetrahydrofolate dehydrogenase (NADP+) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in tetrahydrofolate interconversion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2
Names
putative bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Aptenodytes forsteri Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM69914v1

Genomic

  1. NW_008795298.1 Reference ASM69914v1

    Range
    1226131..1257104 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_009279333.1 → XP_009277608.1  probable bifunctional methylenetetrahydrofolate dehydrogenase/cyclohydrolase 2

    UniProtKB/TrEMBL
    A0A087R264
    Conserved Domains (3) summary
    cd01080
    Location:130 → 309
    NAD_bind_m-THF_DH_Cyclohyd; NADP binding domain of methylene-tetrahydrofolate dehydrogenase/cyclohydrolase
    COG0190
    Location:18 → 310
    FolD; 5,10-methylene-tetrahydrofolate dehydrogenase/Methenyl tetrahydrofolate cyclohydrolase [Coenzyme transport and metabolism]
    pfam00763
    Location:19 → 135
    THF_DHG_CYH; Tetrahydrofolate dehydrogenase/cyclohydrolase, catalytic domain
Nucleotide Protein
Heading Accession and Version

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