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NRG1 neuregulin 1 [ Serinus canaria (Common canary) ]

Gene ID: 103821235, updated on 11-Mar-2024

Summary

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Gene symbol
NRG1
Gene description
neuregulin 1
See related
EnsemblRapid:ENSSCAG00000013380
Gene type
protein coding
RefSeq status
MODEL
Organism
Serinus canaria
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Passeriformes; Passeroidea; Fringillidae; Carduelinae; Serinus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Z
Exon count:
15
Annotation release Status Assembly Chr Location
RS_2023_02 current serCan2020 (GCF_022539315.1) Z NC_066343.1 (31928196..32104410, complement)

Chromosome Z - NC_066343.1Genomic Context describing neighboring genes Neighboring gene E3 ubiquitin-protein ligase KCMF1 Neighboring gene farnesyltransferase, CAAX box, subunit alpha Neighboring gene fucosyltransferase 10 Neighboring gene uncharacterized LOC127061051 Neighboring gene lipoprotein lipase

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_066343.1 Chromosome Z Reference serCan2020 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chemorepellent activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein tyrosine kinase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in activation of transmembrane receptor protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in animal organ development IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in nervous system development IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pro-neuregulin-1, membrane-bound isoform

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_022539315.1-RS_2023_02

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference serCan2020 Primary Assembly

Genomic

  1. NC_066343.1 Reference serCan2020 Primary Assembly

    Range
    31928196..32104410 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_050987240.1 → XP_050843197.1  pro-neuregulin-1, membrane-bound isoform isoform X3

    Related
    ENSSCAP00000018479.2, ENSSCAT00000020661.2

  2. XM_050987239.1 → XP_050843196.1  pro-neuregulin-1, membrane-bound isoform isoform X2

  3. XM_050987238.1 → XP_050843195.1  pro-neuregulin-1, membrane-bound isoform isoform X1

    Related
    ENSSCAP00000018473.2, ENSSCAT00000020654.2

  4. XM_009096077.4 → XP_009094325.1  pro-neuregulin-1, membrane-bound isoform isoform X4

    Conserved Domains (3) summary
    PHA03099
    Location:224 → 313
    PHA03099; epidermal growth factor-like protein (EGF-like protein); Provisional
    cd00054
    Location:232 → 264
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam02158
    Location:306 → 659
    Neuregulin; Neuregulin family

  5. XM_009096076.4 → XP_009094324.1  pro-neuregulin-1, membrane-bound isoform isoform X6

    Conserved Domains (2) summary
    cd00054
    Location:232 → 264
    EGF_CA; Calcium-binding EGF-like domain, present in a large number of membrane-bound and extracellular (mostly animal) proteins. Many of these proteins require calcium for their biological function and calcium-binding sites have been found to be located at the ...
    pfam02158
    Location:314 → 667
    Neuregulin; Neuregulin family

  6. XM_050987241.1 → XP_050843198.1  pro-neuregulin-1, membrane-bound isoform isoform X5

Nucleotide Protein
Heading Accession and Version

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