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PIK3CB phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta [ Merops nubicus (carmine bee-eater) ]

Gene ID: 103781787, updated on 11-Mar-2024

Summary

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Gene symbol
PIK3CB
Gene description
phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit beta
Locus tag
N331_03055
Gene type
protein coding
RefSeq status
MODEL
Organism
Merops nubicus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Coraciiformes; Meropidae; Merops
Orthologs
human mouse all
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Genomic context

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See PIK3CB in Genome Data Viewer
Location:
chromosome: Un
Exon count:
23
Annotation release Status Assembly Chr Location
100 current ASM69184v1 (GCF_000691845.1) Unplaced Scaffold NW_008589175.1 (12322..63974, complement)

NW_008589175.1Genomic Context describing neighboring genes

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_008589175.1 Unplaced Scaffold Reference ASM69184v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 1-phosphatidylinositol-4-phosphate 3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Merops nubicus Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM69184v1

Genomic

  1. NW_008589175.1 Reference ASM69184v1

    Range
    12322..63974 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008949510.1 → XP_008947758.1  phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform

    UniProtKB/TrEMBL
    A0A091R8V2
    Conserved Domains (5) summary
    cd08693
    Location:319 → 496
    C2_PI3K_class_I_beta_delta; C2 domain present in class I beta and delta phosphatidylinositol 3-kinases (PI3Ks)
    cd00872
    Location:533 → 698
    PI3Ka_I; Phosphoinositide 3-kinase (PI3K) class I, accessory domain ; PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3K class I prefer phosphoinositol (4,5) ...
    cd05173
    Location:702 → 1063
    PI3Kc_IA_beta; Catalytic domain of Class IA Phosphoinositide 3-kinase beta
    pfam00794
    Location:175 → 282
    PI3K_rbd; PI3-kinase family, ras-binding domain
    pfam02192
    Location:36 → 111
    PI3K_p85B; PI3-kinase family, p85-binding domain
Nucleotide Protein
Heading Accession and Version

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