U.S. flag

An official website of the United States government

Format

Send to:

Choose Destination

Tlr8 toll like receptor 8 [ Nannospalax galili (Upper Galilee mountains blind mole rat) ]

Gene ID: 103749968, updated on 11-Mar-2024

Summary

Go to the top of the page Help
Gene symbol
Tlr8
Gene description
toll like receptor 8
Gene type
protein coding
RefSeq status
MODEL
Organism
Nannospalax galili
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Spalacidae; Spalacinae; Nannospalax
Orthologs
human mouse all
NEW
Try the new Gene table
Try the new Transcript table

Genomic context

Go to the top of the page Help
Location:
chromosome: Un
Exon count:
3
Annotation release Status Assembly Chr Location
102 current S.galili_v1.0 (GCF_000622305.1) Unplaced Scaffold NW_008355477.1 (1336223..1348626, complement)

NW_008355477.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC115067647 Neighboring gene thymosin beta 4 X-linked Neighboring gene toll like receptor 7 Neighboring gene phosphoribosyl pyrophosphate synthetase 2

Genomic regions, transcripts, and products

Go to the top of the page Help
Genomic Sequence:
NW_008355477 Unplaced Scaffold Reference S.galili_v1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

Go to the top of the pageHelp

GeneRIFs: Gene References Into Functions

General gene information

Go to the top of the page Help

Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables pattern recognition receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in canonical NF-kappaB signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response to virus IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of interleukin-6 production IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in toll-like receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

Go to the top of the page Help
Preferred Names
toll-like receptor 8

NCBI Reference Sequences (RefSeq)

Go to the top of the page Help

NEW Try the new Transcript table

RefSeqs of Annotated Genomes: Nannospalax galili Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference S.galili_v1.0 Primary Assembly

Genomic

  1. NW_008355477.1 Reference S.galili_v1.0 Primary Assembly

    Range
    1336223..1348626 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029556013.1 → XP_029411873.1  toll-like receptor 8

    UniProtKB/TrEMBL
    A0A8C6WC99
    Conserved Domains (6) summary
    PRK15370
    Location:47 → 222
    PRK15370; type III secretion system effector E3 ubiquitin transferase SlrP
    smart00082
    Location:762 → 802
    LRRCT; Leucine rich repeat C-terminal domain
    smart00255
    Location:870 → 1006
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:181 → 736
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00033
    Location:62 → 85
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:359 → 421
    LRR_8; Leucine rich repeat

  2. XM_008852896.3 → XP_008851118.1  toll-like receptor 8

    UniProtKB/TrEMBL
    A0A8C6WC99
    Conserved Domains (6) summary
    PRK15370
    Location:47 → 222
    PRK15370; type III secretion system effector E3 ubiquitin transferase SlrP
    smart00082
    Location:762 → 802
    LRRCT; Leucine rich repeat C-terminal domain
    smart00255
    Location:870 → 1006
    TIR; Toll - interleukin 1 - resistance
    PLN00113
    Location:181 → 736
    PLN00113; leucine-rich repeat receptor-like protein kinase; Provisional
    sd00033
    Location:62 → 85
    LRR_RI; leucine-rich repeat [structural motif]
    pfam13855
    Location:359 → 421
    LRR_8; Leucine rich repeat

RNA

  1. XR_003847027.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

Gene LinkOut

The following LinkOut resources are supplied by external providers. These providers are responsible for maintaining the links.