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Lrp5 LDL receptor related protein 5 [ Nannospalax galili (Upper Galilee mountains blind mole rat) ]

Gene ID: 103744519, updated on 11-Mar-2024

Summary

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Gene symbol
Lrp5
Gene description
LDL receptor related protein 5
See related
Ensembl:ENSNGAG00000013122
Gene type
protein coding
RefSeq status
MODEL
Organism
Nannospalax galili
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Spalacidae; Spalacinae; Nannospalax
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
24
Annotation release Status Assembly Chr Location
102 current S.galili_v1.0 (GCF_000622305.1) Unplaced Scaffold NW_008349072.1 (403580..508277)

NW_008349072.1Genomic Context describing neighboring genes Neighboring gene lysine methyltransferase 5B Neighboring gene chromosome unknown C11orf24 homolog Neighboring gene transfer RNA alanine (anticodon AGC) Neighboring gene protein phosphatase 6 regulatory subunit 3

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_008349072 Unplaced Scaffold Reference S.galili_v1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcriptome sequencing of the blind subterranean mole rat, Spalax galili: utility and potential for the discovery of novel evolutionary patterns. Malik A, et al. PLoS One, 2011. PMID 21857902, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
low-density lipoprotein receptor-related protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nannospalax galili Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference S.galili_v1.0 Primary Assembly

Genomic

  1. NW_008349072.1 Reference S.galili_v1.0 Primary Assembly

    Range
    403580..508277
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_029569998.1 → XP_029425858.1  low-density lipoprotein receptor-related protein 5 isoform X2

    UniProtKB/TrEMBL
    A0A8C6R236
    Conserved Domains (6) summary
    smart00135
    Location:273 → 315
    LY; Low-density lipoprotein-receptor YWTD domain
    cd00112
    Location:1201 → 1235
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd05819
    Location:585 → 621
    NHL; NHL repeat [structural motif]
    pfam00058
    Location:1 → 39
    Ldl_recept_b; Low-density lipoprotein receptor repeat class B
    cl18310
    Location:550 → 743
    NHL; NHL repeat unit of beta-propeller proteins
    pfam14670
    Location:135 → 172
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  2. XM_008846303.2 → XP_008844525.1  low-density lipoprotein receptor-related protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8C6R236
    Related
    ENSNGAP00000010833.1, ENSNGAT00000016375.1
    Conserved Domains (6) summary
    smart00135
    Location:244 → 286
    LY; Low-density lipoprotein-receptor YWTD domain
    cd00112
    Location:1172 → 1206
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd05819
    Location:556 → 592
    NHL; NHL repeat [structural motif]
    pfam00058
    Location:1 → 39
    Ldl_recept_b; Low-density lipoprotein receptor repeat class B
    cl18310
    Location:521 → 714
    NHL; NHL repeat unit of beta-propeller proteins
    pfam14670
    Location:135 → 172
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  3. XM_029569997.1 → XP_029425857.1  low-density lipoprotein receptor-related protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8C6R236
    Related
    ENSNGAP00000010820.1, ENSNGAT00000016362.1
    Conserved Domains (6) summary
    smart00135
    Location:244 → 286
    LY; Low-density lipoprotein-receptor YWTD domain
    cd00112
    Location:1172 → 1206
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd05819
    Location:556 → 592
    NHL; NHL repeat [structural motif]
    pfam00058
    Location:1 → 39
    Ldl_recept_b; Low-density lipoprotein receptor repeat class B
    cl18310
    Location:521 → 714
    NHL; NHL repeat unit of beta-propeller proteins
    pfam14670
    Location:135 → 172
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  4. XM_029569999.1 → XP_029425859.1  low-density lipoprotein receptor-related protein 5 isoform X3

    UniProtKB/TrEMBL
    A0A8C6R236
    Conserved Domains (6) summary
    smart00135
    Location:273 → 315
    LY; Low-density lipoprotein-receptor YWTD domain
    cd00112
    Location:1122 → 1156
    LDLa; Low Density Lipoprotein Receptor Class A domain, a cysteine-rich repeat that plays a central role in mammalian cholesterol metabolism; the receptor protein binds LDL and transports it into cells by endocytosis; 7 successive cysteine-rich repeats of about ...
    cd05819
    Location:585 → 621
    NHL; NHL repeat [structural motif]
    pfam00058
    Location:1 → 39
    Ldl_recept_b; Low-density lipoprotein receptor repeat class B
    cl18310
    Location:550 → 743
    NHL; NHL repeat unit of beta-propeller proteins
    pfam14670
    Location:135 → 172
    FXa_inhibition; Coagulation Factor Xa inhibitory site
Nucleotide Protein
Heading Accession and Version

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