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Crebbp CREB binding protein [ Nannospalax galili (Upper Galilee mountains blind mole rat) ]

Gene ID: 103744441, updated on 11-Mar-2024

Summary

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Gene symbol
Crebbp
Gene description
CREB binding protein
See related
Ensembl:ENSNGAG00000020231
Gene type
protein coding
RefSeq status
MODEL
Organism
Nannospalax galili
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Spalacidae; Spalacinae; Nannospalax
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
31
Annotation release Status Assembly Chr Location
102 current S.galili_v1.0 (GCF_000622305.1) Unplaced Scaffold NW_008330333.1 (1841940..1996998, complement)

NW_008330333.1Genomic Context describing neighboring genes Neighboring gene SLX4 structure-specific endonuclease subunit Neighboring gene deoxyribonuclease 1 Neighboring gene TNF receptor associated protein 1 Neighboring gene adenylate cyclase 9 Neighboring gene small nucleolar RNA SNORA67 Neighboring gene 60S ribosomal protein L23a pseudogene

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_008330333 Unplaced Scaffold Reference S.galili_v1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcriptome sequencing of the blind subterranean mole rat, Spalax galili: utility and potential for the discovery of novel evolutionary patterns. Malik A, et al. PLoS One, 2011. PMID 21857902, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chromatin DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone acetyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of histone acetyltransferase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
CREB-binding protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nannospalax galili Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference S.galili_v1.0 Primary Assembly

Genomic

  1. NW_008330333.1 Reference S.galili_v1.0 Primary Assembly

    Range
    1841940..1996998 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008846197.1 → XP_008844419.1  CREB-binding protein isoform X1

    UniProtKB/TrEMBL
    A0A8C6RP82, A0A8C6RPT4
    Related
    ENSNGAP00000020938.1, ENSNGAT00000026612.1
    Conserved Domains (12) summary
    cd05495
    Location:1088 → 1195
    Bromo_cbp_like; Bromodomain, cbp_like subfamily. Cbp (CREB binding protein or CREBBP) is an acetyltransferase acting on histone, which gives a specific tag for transcriptional activation and also acetylates non-histone proteins. CREBBP binds specifically to ...
    smart00551
    Location:1767 → 1845
    ZnF_TAZ; TAZ zinc finger, present in p300 and CBP
    PHA03247
    Location:682 → 1020
    PHA03247; large tegument protein UL36; Provisional
    COG5076
    Location:942 → 1194
    COG5076; Transcription factor involved in chromatin remodeling, contains bromodomain [Chromatin structure and dynamics / Transcription]
    cd02337
    Location:1706 → 1746
    ZZ_CBP; Zinc finger, ZZ type. Zinc finger present in CBP/p300 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. CREB-binding protein (CBP) is a large multidomain protein that ...
    cd15802
    Location:1207 → 1279
    RING_CBP-p300; atypical RING domain found in CREB-binding protein and p300 histone acetyltransferases
    cd15557
    Location:1281 → 1312
    PHD_CBP_p300; PHD finger found in CREB-binding protein (CBP) and histone acetyltransferase p300
    pfam09606
    Location:1961 → 2425
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam02135
    Location:362 → 429
    zf-TAZ; TAZ zinc finger
    pfam02172
    Location:586 → 666
    KIX; KIX domain
    pfam08214
    Location:1343 → 1554
    HAT_KAT11; Histone acetylation protein
    pfam09030
    Location:2035 → 2115
    Creb_binding; Creb binding

  2. XM_017801517.2 → XP_017657006.1  CREB-binding protein isoform X2

    UniProtKB/TrEMBL
    A0A8C6RPT4
    Conserved Domains (12) summary
    cd05495
    Location:1029 → 1136
    Bromo_cbp_like; Bromodomain, cbp_like subfamily. Cbp (CREB binding protein or CREBBP) is an acetyltransferase acting on histone, which gives a specific tag for transcriptional activation and also acetylates non-histone proteins. CREBBP binds specifically to ...
    smart00551
    Location:1708 → 1786
    ZnF_TAZ; TAZ zinc finger, present in p300 and CBP
    PHA03247
    Location:623 → 961
    PHA03247; large tegument protein UL36; Provisional
    COG5076
    Location:883 → 1135
    COG5076; Transcription factor involved in chromatin remodeling, contains bromodomain [Chromatin structure and dynamics / Transcription]
    cd02337
    Location:1647 → 1687
    ZZ_CBP; Zinc finger, ZZ type. Zinc finger present in CBP/p300 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. CREB-binding protein (CBP) is a large multidomain protein that ...
    cd15802
    Location:1148 → 1220
    RING_CBP-p300; atypical RING domain found in CREB-binding protein and p300 histone acetyltransferases
    cd15557
    Location:1222 → 1253
    PHD_CBP_p300; PHD finger found in CREB-binding protein (CBP) and histone acetyltransferase p300
    pfam09606
    Location:1902 → 2366
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam02135
    Location:303 → 370
    zf-TAZ; TAZ zinc finger
    pfam02172
    Location:527 → 607
    KIX; KIX domain
    pfam08214
    Location:1284 → 1495
    HAT_KAT11; Histone acetylation protein
    pfam09030
    Location:1976 → 2056
    Creb_binding; Creb binding
Nucleotide Protein
Heading Accession and Version

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