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Tln1 talin 1 [ Nannospalax galili (Upper Galilee mountains blind mole rat) ]

Gene ID: 103741540, updated on 11-Mar-2024

Summary

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Gene symbol
Tln1
Gene description
talin 1
See related
Ensembl:ENSNGAG00000004118
Gene type
protein coding
RefSeq status
MODEL
Organism
Nannospalax galili
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Spalacidae; Spalacinae; Nannospalax
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
57
Annotation release Status Assembly Chr Location
102 current S.galili_v1.0 (GCF_000622305.1) Unplaced Scaffold NW_008346082.1 (261366..294567)

NW_008346082.1Genomic Context describing neighboring genes Neighboring gene microseminoprotein, prostate associated Neighboring gene RGP1 homolog, RAB6A GEF complex partner 1 Neighboring gene glucosylceramidase beta 2 Neighboring gene cAMP responsive element binding protein 3 Neighboring gene tropomyosin 2 Neighboring gene U6 spliceosomal RNA Neighboring gene carbonic anhydrase 9

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_008346082 Unplaced Scaffold Reference S.galili_v1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Transcriptome sequencing of the blind subterranean mole rat, Spalax galili: utility and potential for the discovery of novel evolutionary patterns. Malik A, et al. PLoS One, 2011. PMID 21857902, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables integrin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables structural constituent of cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in platelet aggregation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in ruffle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
talin-1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Nannospalax galili Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference S.galili_v1.0 Primary Assembly

Genomic

  1. NW_008346082.1 Reference S.galili_v1.0 Primary Assembly

    Range
    261366..294567
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008842372.2 → XP_008840594.1  talin-1

    UniProtKB/TrEMBL
    A0A8C6QKS7
    Related
    ENSNGAP00000003567.1, ENSNGAT00000005208.1
    Conserved Domains (10) summary
    cd12150
    Location:1654 → 1826
    talin-RS; rod-segment of the talin C-terminal domain
    smart00295
    Location:88 → 313
    B41; Band 4.1 homologues
    smart00307
    Location:2336 → 2532
    ILWEQ; I/LWEQ domain
    COG5281
    Location:717 → 1141
    COG5281; Phage-related minor tail protein [Mobilome: prophages, transposons]
    cd10569
    Location:309 → 400
    FERM_C_Talin; FERM domain C-lobe/F3 of Talin
    pfam08913
    Location:1849 → 1973
    VBS; Vinculin Binding Site
    cd17171
    Location:2 → 85
    FERM_F0_TLN1; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F0 sub-domain, found in Talin-1 (TLN1)
    cd17173
    Location:86 → 197
    FERM_F1_TLN1; FERM (Four.1 protein, Ezrin, Radixin, Moesin) domain, F1 sub-domain, found in Talin-1 (TLN1)
    pfam09141
    Location:491 → 652
    Talin_middle; Talin, middle domain
    cl19756
    Location:822 → 934
    I_LWEQ; I/LWEQ domain
Nucleotide Protein
Heading Accession and Version

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