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EP300 E1A binding protein p300 [ Ursus maritimus (polar bear) ]

Gene ID: 103674159, updated on 11-Mar-2024

Summary

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Gene symbol
EP300
Gene description
E1A binding protein p300
See related
Ensembl:ENSUMAG00000021277
Gene type
protein coding
RefSeq status
MODEL
Organism
Ursus maritimus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus
Orthologs
human mouse all
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Genomic context

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See EP300 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
31
Annotation release Status Assembly Chr Location
101 current ASM1731132v1 (GCF_017311325.1) Unplaced Scaffold NW_024424564.1 (49360208..49438779)
100 previous assembly UrsMar_1.0 (GCF_000687225.1) Unplaced Scaffold NW_007907208.1 (7577752..7655256, complement)

NW_024424564.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC121104359 Neighboring gene uncharacterized LOC103674092 Neighboring gene U6 spliceosomal RNA Neighboring gene small nucleolar RNA U13 Neighboring gene uncharacterized LOC103674091

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chromatin DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone acetyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of histone acetyltransferase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
histone acetyltransferase p300

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ursus maritimus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1731132v1 Primary Assembly

Genomic

  1. NW_024424564.1 Reference ASM1731132v1 Primary Assembly

    Range
    49360208..49438779
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040637591.1 → XP_040493525.1  histone acetyltransferase p300

    UniProtKB/TrEMBL
    A0A452V8Z6, A0A8M1GF51
    Conserved Domains (9) summary
    cd05495
    Location:1052 → 1159
    Bromo_cbp_like; Bromodomain, cbp_like subfamily. Cbp (CREB binding protein or CREBBP) is an acetyltransferase acting on histone, which gives a specific tag for transcriptional activation and also acetylates non-histone proteins. CREBBP binds specifically to ...
    TIGR01628
    Location:647 → 814
    PABP-1234; polyadenylate binding protein, human types 1, 2, 3, 4 family
    smart00551
    Location:1730 → 1808
    ZnF_TAZ; TAZ zinc finger, present in p300 and CBP
    PHA03247
    Location:661 → 1078
    PHA03247; large tegument protein UL36; Provisional
    cd02337
    Location:1669 → 1709
    ZZ_CBP; Zinc finger, ZZ type. Zinc finger present in CBP/p300 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. CREB-binding protein (CBP) is a large multidomain protein that ...
    cd15802
    Location:1171 → 1243
    RING_CBP-p300; atypical RING domain found in CREB-binding protein and p300 histone acetyltransferases
    cd15646
    Location:1244 → 1278
    PHD_p300; PHD finger found in histone acetyltransferase p300
    pfam09606
    Location:1993 → 2355
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam02172
    Location:567 → 647
    KIX; KIX domain
Nucleotide Protein
Heading Accession and Version

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