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NPAS2 neuronal PAS domain protein 2 [ Ursus maritimus (polar bear) ]

Gene ID: 103671742, updated on 11-Mar-2024

Summary

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Gene symbol
NPAS2
Gene description
neuronal PAS domain protein 2
See related
Ensembl:ENSUMAG00000007574
Gene type
protein coding
RefSeq status
MODEL
Organism
Ursus maritimus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus
Orthologs
human mouse all
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Genomic context

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See NPAS2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
23
Annotation release Status Assembly Chr Location
101 current ASM1731132v1 (GCF_017311325.1) Unplaced Scaffold NW_024426774.1 (77362670..77517196)
100 previous assembly UrsMar_1.0 (GCF_000687225.1) Unplaced Scaffold NW_007907179.1 (315434..460922, complement)

NW_024426774.1Genomic Context describing neighboring genes Neighboring gene phosducin like 3 Neighboring gene uncharacterized LOC121101055 Neighboring gene ribosomal protein L31 Neighboring gene TBC1 domain family member 8

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in circadian regulation of gene expression IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of CLOCK-BMAL transcription complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neuronal PAS domain-containing protein 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ursus maritimus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1731132v1 Primary Assembly

Genomic

  1. NW_024426774.1 Reference ASM1731132v1 Primary Assembly

    Range
    77362670..77517196
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040623585.1 → XP_040479519.1  neuronal PAS domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A452TPK9, A0A8M1F7U3
    Conserved Domains (3) summary
    cd19737
    Location:1 → 77
    bHLH-PAS_NPAS2_PASD4; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in neuronal PAS domain-containing protein 2 (NPAS2) and similar proteins
    pfam00989
    Location:84 → 195
    PAS; PAS fold
    pfam14598
    Location:249 → 352
    PAS_11; PAS domain

  2. XM_040623583.1 → XP_040479517.1  neuronal PAS domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A452TPK9, A0A8M1F7U3
    Conserved Domains (3) summary
    cd19737
    Location:1 → 77
    bHLH-PAS_NPAS2_PASD4; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in neuronal PAS domain-containing protein 2 (NPAS2) and similar proteins
    pfam00989
    Location:84 → 195
    PAS; PAS fold
    pfam14598
    Location:249 → 352
    PAS_11; PAS domain

  3. XM_040623586.1 → XP_040479520.1  neuronal PAS domain-containing protein 2 isoform X2

    UniProtKB/TrEMBL
    A0A452TPK9, A0A8M1FBD4
    Conserved Domains (4) summary
    cd19737
    Location:1 → 77
    bHLH-PAS_NPAS2_PASD4; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in neuronal PAS domain-containing protein 2 (NPAS2) and similar proteins
    pfam00989
    Location:84 → 195
    PAS; PAS fold
    pfam14598
    Location:249 → 352
    PAS_11; PAS domain
    cl41773
    Location:422 → 664
    SP1-4_N; N-terminal domain of transcription factor Specificity Proteins (SP) 1-4

  4. XM_040623588.1 → XP_040479522.1  neuronal PAS domain-containing protein 2 isoform X4

    UniProtKB/TrEMBL
    A0A452TPK9, A0A8M1FCB4
    Conserved Domains (4) summary
    smart00091
    Location:84 → 149
    PAS; PAS domain
    PHA03247
    Location:557 → 755
    PHA03247; large tegument protein UL36; Provisional
    pfam08447
    Location:261 → 348
    PAS_3; PAS fold
    cd19737
    Location:1 → 77
    bHLH-PAS_NPAS2_PASD4; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in neuronal PAS domain-containing protein 2 (NPAS2) and similar proteins

  5. XM_040623587.1 → XP_040479521.1  neuronal PAS domain-containing protein 2 isoform X3

    UniProtKB/TrEMBL
    A0A452TPK9, A0A8M1F845
    Conserved Domains (4) summary
    smart00091
    Location:84 → 149
    PAS; PAS domain
    pfam09606
    Location:537 → 765
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    pfam08447
    Location:261 → 348
    PAS_3; PAS fold
    cd19737
    Location:1 → 77
    bHLH-PAS_NPAS2_PASD4; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in neuronal PAS domain-containing protein 2 (NPAS2) and similar proteins

  6. XM_040623584.1 → XP_040479518.1  neuronal PAS domain-containing protein 2 isoform X1

    UniProtKB/TrEMBL
    A0A452TPK9, A0A8M1F7U3
    Conserved Domains (3) summary
    cd19737
    Location:1 → 77
    bHLH-PAS_NPAS2_PASD4; basic helix-loop-helix-Per-ARNT-Sim (bHLH-PAS) domain found in neuronal PAS domain-containing protein 2 (NPAS2) and similar proteins
    pfam00989
    Location:84 → 195
    PAS; PAS fold
    pfam14598
    Location:249 → 352
    PAS_11; PAS domain

  7. XM_040623589.1 → XP_040479523.1  neuronal PAS domain-containing protein 2 isoform X5

    UniProtKB/TrEMBL
    A0A452TPK9, A0A8M1F7U8
    Conserved Domains (1) summary
    pfam08447
    Location:137 → 224
    PAS_3; PAS fold
Nucleotide Protein
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