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LOC103671095 epidermal growth factor receptor kinase substrate 8-like protein 2 [ Ursus maritimus (polar bear) ]

Gene ID: 103671095, updated on 16-Nov-2023

Summary

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Gene symbol
LOC103671095
Gene description
epidermal growth factor receptor kinase substrate 8-like protein 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Ursus maritimus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus
Also known as
EPS8L2
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Genomic context

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Location:
chromosome: Un
Exon count:
31
Annotation release Status Assembly Chr Location
101 current ASM1731132v1 (GCF_017311325.1) Unplaced Scaffold NW_024424786.1 (46997047..47018494, complement)
100 previous assembly UrsMar_1.0 (GCF_000687225.1) Unplaced Scaffold NW_007907177.1 (442909..457625)

NW_024424786.1Genomic Context describing neighboring genes Neighboring gene glutamine amidotransferase class 1 domain containing 1 Neighboring gene transaldolase 1 Neighboring gene epidermal growth factor receptor kinase substrate 8-like protein 2 Neighboring gene transmembrane protein 80 Neighboring gene DEAF1 transcription factor

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Rho protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of ruffle assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of Rho protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in ruffle membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in vesicle IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
epidermal growth factor receptor kinase substrate 8-like protein 2
Names
EPS8 like 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ursus maritimus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1731132v1 Primary Assembly

Genomic

  1. NW_024424786.1 Reference ASM1731132v1 Primary Assembly

    Range
    46997047..47018494 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040638799.1 → XP_040494733.1  epidermal growth factor receptor kinase substrate 8-like protein 2

    UniProtKB/TrEMBL
    A0A8M1GGE4
    Conserved Domains (5) summary
    cd11764
    Location:907 → 958
    SH3_Eps8; Src Homology 3 domain of Epidermal growth factor receptor kinase substrate 8 and similar proteins
    cd01210
    Location:48 → 282
    PTB_EPS8; Epidermal growth factor receptor kinase substrate (EPS8)-like Phosphotyrosine-binding (PTB) domain
    cl15755
    Location:1032 → 1051
    SAM_superfamily; SAM (Sterile alpha motif )
    cl17036
    Location:1052 → 1078
    SH3; Src Homology 3 domain superfamily
    cl17171
    Location:517 → 586
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version

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