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ANXA1 annexin A1 [ Ursus maritimus (polar bear) ]

Gene ID: 103663267, updated on 11-Mar-2024

Summary

Gene symbol
ANXA1
Gene description
annexin A1
See related
Ensembl:ENSUMAG00000022067
Gene type
protein coding
RefSeq status
MODEL
Organism
Ursus maritimus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus
Orthologs
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Genomic context

Location:
chromosome: Un
Exon count:
13
Annotation release Status Assembly Chr Location
101 current ASM1731132v1 (GCF_017311325.1) Unplaced Scaffold NW_024426008.1 (14795529..14812242, complement)
100 previous assembly UrsMar_1.0 (GCF_000687225.1) Unplaced Scaffold NW_007907118.1 (14340040..14356760)

NW_024426008.1Genomic Context describing neighboring genes Neighboring gene U6 spliceosomal RNA Neighboring gene U6 spliceosomal RNA Neighboring gene ATP synthase F(0) complex subunit C2, mitochondrial-like Neighboring gene uncharacterized LOC103663265

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cadherin binding involved in cell-cell adhesion IEA
Inferred from Electronic Annotation
more info
PubMed 
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables calcium-dependent phospholipid binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables phospholipase A2 inhibitor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in DNA duplex unwinding IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in alpha-beta T cell differentiation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in arachidonic acid secretion IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cell surface receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cellular response to glucocorticoid stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cellular response to hydrogen peroxide IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cellular response to vascular endothelial growth factor stimulus IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in endocrine pancreas development IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in estrous cycle IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in gliogenesis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in granulocyte chemotaxis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in hepatocyte differentiation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in inflammatory response IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in insulin secretion IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in keratinocyte differentiation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in myoblast migration involved in skeletal muscle regeneration IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in negative regulation of T-helper 2 cell differentiation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in negative regulation of exocytosis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in negative regulation of phospholipase A2 activity IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in neutrophil clearance IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of G1/S transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of T cell proliferation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of T-helper 1 cell differentiation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of cell migration involved in sprouting angiogenesis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of interleukin-2 production IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of neutrophil apoptotic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of prostaglandin biosynthetic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of vesicle fusion IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in positive regulation of wound healing IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in prolactin secretion IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in prostate gland development IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of cell shape IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of hormone secretion IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of inflammatory response IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of interleukin-1 production IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of leukocyte migration IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in response to X-ray IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in response to estradiol IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in response to interleukin-1 IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in response to peptide hormone IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
PubMed 

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ursus maritimus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1731132v1 Primary Assembly

Genomic

  1. NW_024426008.1 Reference ASM1731132v1 Primary Assembly

    Range
    14795529..14812242 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008690963.2XP_008689185.1  annexin A1

    UniProtKB/TrEMBL
    A0A384C464, A0A452VAQ5
    Related
    ENSUMAP00000030564.1
    Conserved Domains (1) summary
    pfam00191
    Location:277342
    Annexin; Annexin