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GRIA4 glutamate ionotropic receptor AMPA type subunit 4 [ Ursus maritimus (polar bear) ]

Gene ID: 103662439, updated on 11-Mar-2024

Summary

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Gene symbol
GRIA4
Gene description
glutamate ionotropic receptor AMPA type subunit 4
See related
Ensembl:ENSUMAG00000008904
Gene type
protein coding
RefSeq status
MODEL
Organism
Ursus maritimus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
18
Annotation release Status Assembly Chr Location
101 current ASM1731132v1 (GCF_017311325.1) Unplaced Scaffold NW_024424008.1 (59883190..60238828, complement)
100 previous assembly UrsMar_1.0 (GCF_000687225.1) Unplaced Scaffold NW_007907111.1 (15181380..15537279, complement)

NW_024424008.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103662435 Neighboring gene Myb/SANT DNA binding domain containing 4 with coiled-coils Neighboring gene 60 kDa heat shock protein, mitochondrial-like Neighboring gene uncharacterized LOC103662444 Neighboring gene caspase-1 Neighboring gene transfer RNA glutamic acid (anticodon CUC)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables AMPA glutamate receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmitter-gated monoatomic ion channel activity involved in regulation of postsynaptic membrane potential IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in modulation of chemical synaptic transmission IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in monoatomic ion transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in synaptic transmission, glutamatergic IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of AMPA glutamate receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in dendritic spine IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in postsynaptic membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
glutamate receptor 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ursus maritimus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1731132v1 Primary Assembly

Genomic

  1. NW_024424008.1 Reference ASM1731132v1 Primary Assembly

    Range
    59883190..60238828 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008690134.1 → XP_008688356.1  glutamate receptor 4 isoform X4

    See identical proteins and their annotated locations for XP_008688356.1

    UniProtKB/TrEMBL
    A0A384C0F1
    Related
    ENSUMAP00000012027.1, ENSUMAT00000014306.1
    Conserved Domains (2) summary
    cd06388
    Location:28 → 398
    PBP1_iGluR_AMPA_GluR4; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the GluR4 subunit of the AMPA receptor
    cd13727
    Location:414 → 795
    PBP2_iGluR_AMPA_GluR4; The ligand-binding domain of the AMPA (alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid) subtype GluR4 of ionotropic glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily

  2. XM_008690131.1 → XP_008688353.1  glutamate receptor 4 isoform X1

    See identical proteins and their annotated locations for XP_008688353.1

    UniProtKB/TrEMBL
    A0A384C0J3
    Related
    ENSUMAP00000012032.1, ENSUMAT00000014312.1
    Conserved Domains (2) summary
    cd13727
    Location:414 → 795
    PBP2_iGluR_AMPA_GluR4; The ligand-binding domain of the AMPA (alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid) subtype GluR4 of ionotropic glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
    cd06388
    Location:28 → 400
    PBP1_iGluR_AMPA_GluR4; N-terminal leucine-isoleucine-valine binding protein (LIVBP)-like domain of the GluR4 subunit of the AMPA receptor

  3. XM_008690132.1 → XP_008688354.1  glutamate receptor 4 isoform X3

    UniProtKB/TrEMBL
    A0A384C1Q0
    Conserved Domains (4) summary
    cd06388
    Location:28 → 400
    PBP1_iGluR_AMPA_GluR4; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the GluR4 subunit of the AMPA receptor
    cd13727
    Location:416 → 797
    PBP2_iGluR_AMPA_GluR4; The ligand-binding domain of the AMPA (alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid) subtype GluR4 of ionotropic glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
    pfam00060
    Location:548 → 827
    Lig_chan; Ligand-gated ion channel
    pfam01094
    Location:39 → 382
    ANF_receptor; Receptor family ligand binding region

  4. XM_008690133.1 → XP_008688355.1  glutamate receptor 4 isoform X2

    UniProtKB/TrEMBL
    A0A384C1R3
    Conserved Domains (4) summary
    cd06388
    Location:28 → 400
    PBP1_iGluR_AMPA_GluR4; N-terminal leucine/isoleucine/valine-binding protein (LIVBP)-like domain of the GluR4 subunit of the AMPA receptor
    cd13727
    Location:416 → 797
    PBP2_iGluR_AMPA_GluR4; The ligand-binding domain of the AMPA (alpha-amino-3-hydroxyl-5-methyl-4-isoxazolepropionic acid) subtype GluR4 of ionotropic glutamate receptors, a member of the type 2 periplasmic binding fold protein superfamily
    pfam00060
    Location:548 → 827
    Lig_chan; Ligand-gated ion channel
    pfam01094
    Location:39 → 382
    ANF_receptor; Receptor family ligand binding region

  5. XM_008690135.1 → XP_008688357.1  glutamate receptor 4 isoform X5

    See identical proteins and their annotated locations for XP_008688357.1

    UniProtKB/TrEMBL
    A0A384C0J6
    Related
    ENSUMAP00000012034.1, ENSUMAT00000014314.1
    Conserved Domains (1) summary
    cd06388
    Location:28 → 400
    PBP1_iGluR_AMPA_GluR4; N-terminal leucine-isoleucine-valine binding protein (LIVBP)-like domain of the GluR4 subunit of the AMPA receptor
Nucleotide Protein
Heading Accession and Version

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