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CTSH cathepsin H [ Ursus maritimus (polar bear) ]

Gene ID: 103660296, updated on 11-Mar-2024

Summary

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Gene symbol
CTSH
Gene description
cathepsin H
Gene type
protein coding
RefSeq status
MODEL
Organism
Ursus maritimus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
12
Annotation release Status Assembly Chr Location
101 current ASM1731132v1 (GCF_017311325.1) Unplaced Scaffold NW_024425230.1 (26012362..26026686)
100 previous assembly UrsMar_1.0 (GCF_000687225.1) Unplaced Scaffold NW_007907086.1 (7373718..7389722)

NW_024425230.1Genomic Context describing neighboring genes Neighboring gene ankyrin repeat domain 34C Neighboring gene Ras protein specific guanine nucleotide releasing factor 1 Neighboring gene U1 spliceosomal RNA Neighboring gene mortality factor 4 like 1 Neighboring gene transfer RNA lysine (anticodon CUU)

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis involved in protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in lysosome IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
pro-cathepsin H

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ursus maritimus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1731132v1 Primary Assembly

Genomic

  1. NW_024425230.1 Reference ASM1731132v1 Primary Assembly

    Range
    26012362..26026686
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040642901.1 → XP_040498835.1  pro-cathepsin H

    UniProtKB/TrEMBL
    A0A452U2J3, A0A8M1GUL8
    Conserved Domains (2) summary
    smart00848
    Location:35 → 89
    Inhibitor_I29; Cathepsin propeptide inhibitor domain (I29)
    cd02248
    Location:117 → 331
    Peptidase_C1A; Peptidase C1A subfamily (MEROPS database nomenclature); composed of cysteine peptidases (CPs) similar to papain, including the mammalian CPs (cathepsins B, C, F, H, L, K, O, S, V, X and W). Papain is an endopeptidase with specific substrate preferences, ...
Nucleotide Protein
Heading Accession and Version

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