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STAT1 signal transducer and activator of transcription 1 [ Ursus maritimus (polar bear) ]

Gene ID: 103659933, updated on 11-Apr-2024

Summary

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Gene symbol
STAT1
Gene description
signal transducer and activator of transcription 1
See related
Ensembl:ENSUMAG00000019696
Gene type
protein coding
RefSeq status
MODEL
Organism
Ursus maritimus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus
Orthologs
human mouse all
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Genomic context

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See STAT1 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
30
Annotation release Status Assembly Chr Location
101 current ASM1731132v1 (GCF_017311325.1) Unplaced Scaffold NW_024423343.1 (42402164..42452738)
100 previous assembly UrsMar_1.0 (GCF_000687225.1) Unplaced Scaffold NW_007907079.1 (36296566..36337597, complement)

NW_024423343.1Genomic Context describing neighboring genes Neighboring gene myosin IB Neighboring gene transfer RNA lysine (anticodon CUU) Neighboring gene signal transducer and activator of transcription 4 Neighboring gene uncharacterized LOC121105529 Neighboring gene serine protease 58-like Neighboring gene glutaminase Neighboring gene U6 spliceosomal RNA Neighboring gene NGFI-A binding protein 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell surface receptor signaling pathway via JAK-STAT IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in defense response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of cell population proliferation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in response to peptide hormone IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in type I interferon-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
signal transducer and activator of transcription 1-alpha/beta

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ursus maritimus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1731132v1 Primary Assembly

Genomic

  1. NW_024423343.1 Reference ASM1731132v1 Primary Assembly

    Range
    42402164..42452738
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040642644.1 → XP_040498578.1  signal transducer and activator of transcription 1-alpha/beta isoform X2

    UniProtKB/TrEMBL
    A0A452V3G9, A0A8M1GS83
    Conserved Domains (5) summary
    cd10372
    Location:616 → 766
    SH2_STAT1; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 1 proteins
    smart00964
    Location:61 → 180
    STAT_int; STAT protein, protein interaction domain
    cd16851
    Location:197 → 372
    STAT1_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 1 (STAT1)
    cd16845
    Location:376 → 536
    STAT1_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 1 (STAT1)
    pfam12162
    Location:774 → 798
    STAT1_TAZ2bind; STAT1 TAZ2 binding domain

  2. XM_040642640.1 → XP_040498574.1  signal transducer and activator of transcription 1-alpha/beta isoform X1

    UniProtKB/TrEMBL
    A0A452V3G9, A0A8M1H3L6
    Conserved Domains (5) summary
    cd10372
    Location:616 → 766
    SH2_STAT1; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 1 proteins
    smart00964
    Location:61 → 180
    STAT_int; STAT protein, protein interaction domain
    cd16851
    Location:197 → 372
    STAT1_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 1 (STAT1)
    cd16845
    Location:376 → 536
    STAT1_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 1 (STAT1)
    pfam12162
    Location:774 → 798
    STAT1_TAZ2bind; STAT1 TAZ2 binding domain

  3. XM_040642669.1 → XP_040498603.1  signal transducer and activator of transcription 1-alpha/beta isoform X3

    UniProtKB/TrEMBL
    A0A452V3G9, A0A8M1GSA7
    Conserved Domains (5) summary
    cd10372
    Location:557 → 707
    SH2_STAT1; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 1 proteins
    smart00964
    Location:2 → 121
    STAT_int; STAT protein, protein interaction domain
    cd16851
    Location:138 → 313
    STAT1_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 1 (STAT1)
    cd16845
    Location:317 → 477
    STAT1_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 1 (STAT1)
    pfam12162
    Location:715 → 739
    STAT1_TAZ2bind; STAT1 TAZ2 binding domain

  4. XM_040642660.1 → XP_040498594.1  signal transducer and activator of transcription 1-alpha/beta isoform X3

    UniProtKB/TrEMBL
    A0A452V3G9, A0A8M1GSA7
    Conserved Domains (5) summary
    cd10372
    Location:557 → 707
    SH2_STAT1; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 1 proteins
    smart00964
    Location:2 → 121
    STAT_int; STAT protein, protein interaction domain
    cd16851
    Location:138 → 313
    STAT1_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 1 (STAT1)
    cd16845
    Location:317 → 477
    STAT1_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 1 (STAT1)
    pfam12162
    Location:715 → 739
    STAT1_TAZ2bind; STAT1 TAZ2 binding domain

  5. XM_040642663.1 → XP_040498597.1  signal transducer and activator of transcription 1-alpha/beta isoform X3

    UniProtKB/TrEMBL
    A0A452V3G9, A0A8M1GSA7
    Conserved Domains (5) summary
    cd10372
    Location:557 → 707
    SH2_STAT1; Src homology 2 (SH2) domain found in signal transducer and activator of transcription (STAT) 1 proteins
    smart00964
    Location:2 → 121
    STAT_int; STAT protein, protein interaction domain
    cd16851
    Location:138 → 313
    STAT1_CCD; Coiled-coil domain of Signal Transducer and Activator of Transcription 1 (STAT1)
    cd16845
    Location:317 → 477
    STAT1_DBD; DNA-binding domain of Signal Transducer and Activator of Transcription 1 (STAT1)
    pfam12162
    Location:715 → 739
    STAT1_TAZ2bind; STAT1 TAZ2 binding domain

RNA

  1. XR_005838025.1 RNA Sequence

  2. XR_005838027.1 RNA Sequence

  3. XR_005838026.1 RNA Sequence

Nucleotide Protein
Heading Accession and Version

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