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GSDMD gasdermin D [ Ursus maritimus (polar bear) ]

Gene ID: 103656671, updated on 11-Mar-2024

Summary

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Gene symbol
GSDMD
Gene description
gasdermin D
See related
Ensembl:ENSUMAG00000001062
Gene type
protein coding
RefSeq status
MODEL
Organism
Ursus maritimus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Ursidae; Ursus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
11
Annotation release Status Assembly Chr Location
101 current ASM1731132v1 (GCF_017311325.1) Unplaced Scaffold NW_024427107.1 (79677196..79682100)
100 previous assembly UrsMar_1.0 (GCF_000687225.1) Unplaced Scaffold NW_007930776.1 (1098796..1103730, complement)

NW_024427107.1Genomic Context describing neighboring genes Neighboring gene MAF bZIP transcription factor A Neighboring gene zinc finger CCCH-type containing 3 Neighboring gene maestro heat like repeat family member 6 Neighboring gene nicotinate phosphoribosyltransferase

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables phosphatidylinositol-4,5-bisphosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol-4-phosphate binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylserine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in defense response to bacterium IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in pyroptosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of NLRP3 inflammasome complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
gasdermin-D

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Ursus maritimus Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM1731132v1 Primary Assembly

Genomic

  1. NW_024427107.1 Reference ASM1731132v1 Primary Assembly

    Range
    79677196..79682100
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_040626065.1 → XP_040481999.1  gasdermin-D isoform X3

    UniProtKB/TrEMBL
    A0A8M1FND6

  2. XM_008684088.2 → XP_008682310.1  gasdermin-D isoform X4

    UniProtKB/TrEMBL
    A0A384BJK3
    Conserved Domains (1) summary
    pfam04598
    Location:104 → 444
    Gasdermin; Gasdermin family

  3. XM_040626064.1 → XP_040481998.1  gasdermin-D isoform X1

    UniProtKB/TrEMBL
    A0A8M1FF29

  4. XM_008684087.2 → XP_008682309.1  gasdermin-D isoform X2

    UniProtKB/TrEMBL
    A0A384BJ67
    Related
    ENSUMAP00000001052.1
    Conserved Domains (1) summary
    pfam04598
    Location:104 → 550
    Gasdermin; Gasdermin family
Nucleotide Protein
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