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ARHGEF2 Rho/Rac guanine nucleotide exchange factor 2 [ Corvus brachyrhynchos (American crow) ]

Gene ID: 103619597, updated on 11-Mar-2024

Summary

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Gene symbol
ARHGEF2
Gene description
Rho/Rac guanine nucleotide exchange factor 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Corvus brachyrhynchos
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Passeriformes; Corvoidea; Corvidae; Corvus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
13
Annotation release Status Assembly Chr Location
101 current ASM69197v1 (GCF_000691975.1) Unplaced Scaffold NW_008239142.1 (321767..326994)

NW_008239142.1Genomic Context describing neighboring genes Neighboring gene ribosomal protein S27 Neighboring gene cathepsin S Neighboring gene uncharacterized LOC108448115 Neighboring gene uncharacterized LOC108448118

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_008239142.1 Unplaced Scaffold Reference ASM69197v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin filament organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell morphogenesis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of neuron differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of Rho protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in ruffle membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho guanine nucleotide exchange factor 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Corvus brachyrhynchos Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM69197v1

Genomic

  1. NW_008239142.1 Reference ASM69197v1

    Range
    321767..326994
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008638146.2 → XP_008636368.1  rho guanine nucleotide exchange factor 2 isoform X1

    Conserved Domains (4) summary
    cd00029
    Location:15 → 60
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    pfam00169
    Location:457 → 550
    PH; PH domain
    pfam00621
    Location:215 → 407
    RhoGEF; RhoGEF domain
    cl17171
    Location:449 → 551
    PH-like; Pleckstrin homology-like domain

  2. XM_017740072.1 → XP_017595561.1  rho guanine nucleotide exchange factor 2 isoform X3

  3. XM_017740071.1 → XP_017595560.1  rho guanine nucleotide exchange factor 2 isoform X2

    Conserved Domains (4) summary
    cd00029
    Location:15 → 60
    C1; Protein kinase C conserved region 1 (C1) . Cysteine-rich zinc binding domain. Some members of this domain family bind phorbol esters and diacylglycerol, some are reported to bind RasGTP. May occur in tandem arrangement. Diacylglycerol (DAG) is a second ...
    pfam00169
    Location:457 → 550
    PH; PH domain
    pfam00621
    Location:215 → 407
    RhoGEF; RhoGEF domain
    cl17171
    Location:449 → 551
    PH-like; Pleckstrin homology-like domain

  4. XM_017740073.1 → XP_017595562.1  rho guanine nucleotide exchange factor 2 isoform X4

Nucleotide Protein
Heading Accession and Version

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