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DHFR dihydrofolate reductase [ Corvus brachyrhynchos (American crow) ]

Gene ID: 103618976, updated on 11-Mar-2024

Summary

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Gene symbol
DHFR
Gene description
dihydrofolate reductase
Locus tag
N302_01077
Gene type
protein coding
RefSeq status
MODEL
Organism
Corvus brachyrhynchos
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Passeriformes; Corvoidea; Corvidae; Corvus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
5
Annotation release Status Assembly Chr Location
101 current ASM69197v1 (GCF_000691975.1) Unplaced Scaffold NW_008239003.1 (134200..146251, complement)

NW_008239003.1Genomic Context describing neighboring genes Neighboring gene family with sequence similarity 151 member B Neighboring gene ankyrin repeat domain 34B Neighboring gene mutS homolog 3 Neighboring gene uncharacterized LOC108447846

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_008239003.1 Unplaced Scaffold Reference ASM69197v1

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables NADP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables dihydrofolate reductase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in dihydrofolate metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in folic acid metabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in glycine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tetrahydrofolate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in mitochondrion IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
dihydrofolate reductase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Corvus brachyrhynchos Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM69197v1

Genomic

  1. NW_008239003.1 Reference ASM69197v1

    Range
    134200..146251 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008637449.2 → XP_008635671.1  dihydrofolate reductase

    See identical proteins and their annotated locations for XP_008635671.1

    UniProtKB/TrEMBL
    A0A091F0C8
    Conserved Domains (1) summary
    cd00209
    Location:12 → 147
    DHFR; Dihydrofolate reductase (DHFR). Reduces 7,8-dihydrofolate to 5,6,7,8-tetrahydrofolate with NADPH as a cofactor. This is an essential step in the biosynthesis of deoxythymidine phosphate since 5,6,7,8-tetrahydrofolate is required to regenerate 5, ...
Nucleotide Protein
Heading Accession and Version

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