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SPTBN2 spectrin beta, non-erythrocytic 2 [ Equus przewalskii (Przewalski's horse) ]

Gene ID: 103559772, updated on 11-Mar-2024

Summary

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Gene symbol
SPTBN2
Gene description
spectrin beta, non-erythrocytic 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus przewalskii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
39
Annotation release Status Assembly Chr Location
100 current Burgud (GCF_000696695.1) Unplaced Scaffold NW_007673080.1 (800357..838131, complement)

NW_007673080.1Genomic Context describing neighboring genes Neighboring gene RNA-binding protein 14 Neighboring gene copper chaperone for superoxide dismutase Neighboring gene RNA-binding protein 4B Neighboring gene TOP6B like initiator of meiotic double strand breaks Neighboring gene Ras converting CAAX endopeptidase 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_007673080 unplaced scaffold reference Burgud Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phospholipid binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables structural constituent of cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cell junction IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cell projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cortical actin cytoskeleton IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of spectrin IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
spectrin beta chain, non-erythrocytic 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Equus przewalskii Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Burgud Primary Assembly

Genomic

  1. NW_007673080.1 Reference Burgud Primary Assembly

    Range
    800357..838131 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008533535.1 → XP_008531757.1  spectrin beta chain, non-erythrocytic 2 isoform X3

    Conserved Domains (7) summary
    smart00150
    Location:2018 → 2075
    SPEC; Spectrin repeats
    smart00033
    Location:61 → 159
    CH; Calponin homology domain
    cd00014
    Location:177 → 280
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00176
    Location:1384 → 1588
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd10571
    Location:2221 → 2324
    PH_beta_spectrin; Beta-spectrin pleckstrin homology (PH) domain
    pfam00169
    Location:2221 → 2324
    PH; PH domain
    pfam00435
    Location:429 → 522
    Spectrin; Spectrin repeat

  2. XM_008533516.1 → XP_008531738.1  spectrin beta chain, non-erythrocytic 2 isoform X1

    Conserved Domains (7) summary
    smart00150
    Location:2044 → 2101
    SPEC; Spectrin repeats
    smart00033
    Location:87 → 185
    CH; Calponin homology domain
    cd00014
    Location:203 → 306
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00176
    Location:1410 → 1614
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd10571
    Location:2247 → 2350
    PH_beta_spectrin; Beta-spectrin pleckstrin homology (PH) domain
    pfam00169
    Location:2247 → 2350
    PH; PH domain
    pfam00435
    Location:455 → 548
    Spectrin; Spectrin repeat

  3. XM_008533525.1 → XP_008531747.1  spectrin beta chain, non-erythrocytic 2 isoform X2

    Conserved Domains (7) summary
    smart00150
    Location:2025 → 2082
    SPEC; Spectrin repeats
    smart00033
    Location:68 → 166
    CH; Calponin homology domain
    cd00014
    Location:184 → 287
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00176
    Location:1391 → 1595
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd10571
    Location:2228 → 2331
    PH_beta_spectrin; Beta-spectrin pleckstrin homology (PH) domain
    pfam00169
    Location:2228 → 2331
    PH; PH domain
    pfam00435
    Location:436 → 529
    Spectrin; Spectrin repeat
Nucleotide Protein
Heading Accession and Version

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