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IQGAP3 IQ motif containing GTPase activating protein 3 [ Equus przewalskii (Przewalski's horse) ]

Gene ID: 103548855, updated on 11-Mar-2024

Summary

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Gene symbol
IQGAP3
Gene description
IQ motif containing GTPase activating protein 3
Gene type
protein coding
RefSeq status
MODEL
Organism
Equus przewalskii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Perissodactyla; Equidae; Equus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
38
Annotation release Status Assembly Chr Location
100 current Burgud (GCF_000696695.1) Unplaced Scaffold NW_007673341.1 (737009..776135, complement)

NW_007673341.1Genomic Context describing neighboring genes Neighboring gene MIR9-1 host gene Neighboring gene myocyte enhancer factor 2D Neighboring gene tetratricopeptide repeat domain 24 Neighboring gene NAD(P)HX epimerase

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_007673341 unplaced scaffold reference Burgud Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables actin filament binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables calmodulin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of actin cytoskeleton organization IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ras GTPase-activating-like protein IQGAP3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Equus przewalskii Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Burgud Primary Assembly

Genomic

  1. NW_007673341.1 Reference Burgud Primary Assembly

    Range
    737009..776135 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008516840.1 → XP_008515062.1  ras GTPase-activating-like protein IQGAP3

    Conserved Domains (6) summary
    smart00015
    Location:746 → 763
    IQ; Calmodulin-binding motif
    cd12207
    Location:970 → 1319
    RasGAP_IQGAP3; Ras-GTPase Activating Domain of IQ motif containing GTPase activating protein 3
    smart00323
    Location:959 → 1310
    RasGAP; GTPase-activator protein for Ras-like GTPases
    cd00014
    Location:35 → 147
    CH; Calponin homology domain; actin-binding domain which may be present as a single copy or in tandem repeats (which increases binding affinity). The CH domain is found in cytoskeletal and signal transduction proteins, including actin-binding proteins like ...
    cd00201
    Location:653 → 680
    WW; Two conserved tryptophans domain; also known as the WWP or rsp5 domain; around 40 amino acids; functions as an interaction module in a diverse set of signalling proteins; binds specific proline-rich sequences but at low affinities compared to other ...
    pfam03836
    Location:1431 → 1537
    RasGAP_C; RasGAP C-terminus
Nucleotide Protein
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