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MCF2L MCF.2 cell line derived transforming sequence like [ Calypte anna (Anna's hummingbird) ]

Gene ID: 103525637, updated on 11-Mar-2024

Summary

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Gene symbol
MCF2L
Gene description
MCF.2 cell line derived transforming sequence like
Locus tag
N300_13861
See related
EnsemblRapid:ENSCAAG00010015458
Gene type
protein coding
RefSeq status
MODEL
Organism
Calypte anna
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Archosauria; Dinosauria; Saurischia; Theropoda; Coelurosauria; Aves; Neognathae; Caprimulgimorphae; Apodiformes; Trochilidae; Calypte
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 1
Exon count:
34
Annotation release Status Assembly Chr Location
101 current bCalAnn1_v1.p (GCF_003957555.1) 1 NC_044244.1 (139513034..139612665, complement)
100 previous assembly ASM69908v1 (GCF_000699085.1) Unplaced Scaffold NW_007619259.1 (2112..156800, complement)

Chromosome 1 - NC_044244.1Genomic Context describing neighboring genes Neighboring gene coagulation factor X Neighboring gene coagulation factor VII Neighboring gene U6 spliceosomal RNA Neighboring gene ATPase phospholipid transporting 11A

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of Rho protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extrinsic component of membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
guanine nucleotide exchange factor DBS
Names
Guanine nucleotide exchange factor DBS

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Calypte anna Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference bCalAnn1_v1.p

Genomic

  1. NC_044244.1 Reference bCalAnn1_v1.p

    Range
    139513034..139612665 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_030468267.1 → XP_030324127.1  guanine nucleotide exchange factor DBS isoform X1

    Related
    ENSCAAP00010021271.1, ENSCAAT00010022776.1
    Conserved Domains (5) summary
    cd11857
    Location:1117 → 1171
    SH3_DBS; Src homology 3 domain of DBL's Big Sister (DBS), a guanine nucleotide exchange factor
    smart00516
    Location:60 → 205
    SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
    cd00160
    Location:616 → 793
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd00176
    Location:336 → 538
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd01227
    Location:800 → 931
    PH_Dbs; DBL's big sister protein pleckstrin homology (PH) domain

  2. XM_030468290.1 → XP_030324150.1  guanine nucleotide exchange factor DBS isoform X2

    Related
    ENSCAAP00010021258.1, ENSCAAT00010022763.1
    Conserved Domains (5) summary
    cd11857
    Location:955 → 1009
    SH3_DBS; Src homology 3 domain of DBL's Big Sister (DBS), a guanine nucleotide exchange factor
    smart00516
    Location:25 → 116
    SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
    cd00160
    Location:527 → 704
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd00176
    Location:247 → 449
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd01227
    Location:711 → 842
    PH_Dbs; DBL's big sister protein pleckstrin homology (PH) domain
Nucleotide Protein
Heading Accession and Version

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