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nox4 NADPH oxidase 4 [ Poecilia reticulata (guppy) ]

Gene ID: 103474485, updated on 11-Mar-2024

Summary

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Gene symbol
nox4
Gene description
NADPH oxidase 4
See related
Ensembl:ENSPREG00000019643
Gene type
protein coding
RefSeq status
MODEL
Organism
Poecilia reticulata
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae; Poecilia
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: LG13
Exon count:
18
Annotation release Status Assembly LG Location
101 current Guppy_female_1.0+MT (GCF_000633615.1) LG13 NC_024343.1 (12593105..12613117)

Linkage Group LG13 - NC_024343.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC103474482 Neighboring gene N-acetylated alpha-linked acidic dipeptidase 2 Neighboring gene tyrosinase Neighboring gene glutamate receptor, metabotropic 5b

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_024343.1 Chromosome LG13 Reference Guppy_female_1.0+MT Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables superoxide-generating NAD(P)H oxidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in defense response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in superoxide anion generation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of NADPH oxidase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
NADPH oxidase 4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Poecilia reticulata Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Guppy_female_1.0+MT Primary Assembly

Genomic

  1. NC_024343.1 Reference Guppy_female_1.0+MT Primary Assembly

    Range
    12593105..12613117
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008425494.1 → XP_008423716.1  NADPH oxidase 4

    UniProtKB/TrEMBL
    A0A3P9Q4V0
    Related
    ENSPREP00000029029.1, ENSPRET00000029350.1
    Conserved Domains (2) summary
    cd06186
    Location:292 → 558
    NOX_Duox_like_FAD_NADP; NADPH oxidase (NOX) catalyzes the generation of reactive oxygen species (ROS) such as superoxide and hydrogen peroxide. ROS were originally identified as bactericidal agents in phagocytes, but are now also implicated in cell signaling and metabolism. NOX ...
    pfam01794
    Location:61 → 204
    Ferric_reduct; Ferric reductase like transmembrane component
Nucleotide Protein
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