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mthfr methylenetetrahydrofolate reductase (NAD(P)H) [ Poecilia reticulata (guppy) ]

Gene ID: 103466998, updated on 11-Mar-2024

Summary

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Gene symbol
mthfr
Gene description
methylenetetrahydrofolate reductase (NAD(P)H)
See related
Ensembl:ENSPREG00000009194
Gene type
protein coding
RefSeq status
MODEL
Organism
Poecilia reticulata
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae; Poecilia
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: LG7
Exon count:
12
Annotation release Status Assembly LG Location
101 current Guppy_female_1.0+MT (GCF_000633615.1) LG7 NC_024337.1 (5449352..5458355, complement)

Linkage Group LG7 - NC_024337.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC108166406 Neighboring gene solute carrier family 2, facilitated glucose transporter member 1-like Neighboring gene galactose-specific lectin nattectin-like Neighboring gene voltage-gated potassium channel subunit beta-2-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_024337.1 Chromosome LG7 Reference Guppy_female_1.0+MT Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables FAD binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables methylenetetrahydrofolate reductase (NAD(P)H) activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in methionine biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in tetrahydrofolate interconversion IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
methylenetetrahydrofolate reductase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Poecilia reticulata Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Guppy_female_1.0+MT Primary Assembly

Genomic

  1. NC_024337.1 Reference Guppy_female_1.0+MT Primary Assembly

    Range
    5449352..5458355 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_017305592.1 → XP_017161081.1  methylenetetrahydrofolate reductase

    UniProtKB/TrEMBL
    A0A3P9NVC8, A0A3P9NVP0
    Conserved Domains (1) summary
    cl00246
    Location:64 → 588
    MTHFR; Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase ...

  2. XM_008413006.2 → XP_008411228.1  methylenetetrahydrofolate reductase

    See identical proteins and their annotated locations for XP_008411228.1

    UniProtKB/TrEMBL
    A0A3P9NVC8, A0A3P9NVP0
    Related
    ENSPREP00000013538.1, ENSPRET00000013678.1
    Conserved Domains (1) summary
    cl00246
    Location:64 → 588
    MTHFR; Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase ...

  3. XM_008413005.2 → XP_008411227.1  methylenetetrahydrofolate reductase

    See identical proteins and their annotated locations for XP_008411227.1

    UniProtKB/TrEMBL
    A0A3P9NVC8, A0A3P9NVP0
    Related
    ENSPREP00000013529.1, ENSPRET00000013669.1
    Conserved Domains (1) summary
    cl00246
    Location:64 → 588
    MTHFR; Methylenetetrahydrofolate reductase (MTHFR). 5,10-Methylenetetrahydrofolate is reduced to 5-methyltetrahydrofolate by methylenetetrahydrofolate reductase, a cytoplasmic, NAD(P)-dependent enzyme. 5-methyltetrahydrofolate is utilized by methionine synthase ...
Nucleotide Protein
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