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epha8 eph receptor A8 [ Poecilia reticulata (guppy) ]

Gene ID: 103465441, updated on 11-Apr-2024

Summary

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Gene symbol
epha8
Gene description
eph receptor A8
See related
Ensembl:ENSPREG00000018454
Gene type
protein coding
RefSeq status
MODEL
Organism
Poecilia reticulata
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Ovalentaria; Atherinomorphae; Cyprinodontiformes; Poeciliidae; Poeciliinae; Poecilia
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: LG5
Exon count:
20
Annotation release Status Assembly LG Location
101 current Guppy_female_1.0+MT (GCF_000633615.1) LG5 NC_024335.1 (28515148..28645308)

Linkage Group LG5 - NC_024335.1Genomic Context describing neighboring genes Neighboring gene Krueppel-like factor 15 Neighboring gene nuclear casein kinase and cyclin-dependent kinase substrate 1a Neighboring gene uncharacterized protein PFB0765w-like Neighboring gene claudin 19

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_024335.1 Chromosome LG5 Reference Guppy_female_1.0+MT Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transmembrane-ephrin receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in axon guidance IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in neuron projection IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ephrin type-A receptor 8

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Poecilia reticulata Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Guppy_female_1.0+MT Primary Assembly

Genomic

  1. NC_024335.1 Reference Guppy_female_1.0+MT Primary Assembly

    Range
    28515148..28645308
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008410260.2 → XP_008408482.1  ephrin type-A receptor 8 isoform X1

    UniProtKB/TrEMBL
    A0A3P9Q3S1
    Conserved Domains (7) summary
    cd09550
    Location:959 → 1023
    SAM_EPH-A8; SAM domain of EPH-A8 subfamily of tyrosine kinase receptors
    smart00454
    Location:955 → 1022
    SAM; Sterile alpha motif
    cd00063
    Location:467 → 558
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:657 → 929
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam07714
    Location:662 → 925
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:575 → 657
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    cl02704
    Location:29 → 201
    EphR_LBD; Ligand Binding Domain of Ephrin Receptors

  2. XM_008410262.2 → XP_008408484.1  ephrin type-A receptor 8 isoform X3

    UniProtKB/TrEMBL
    A0A3P9Q3S2
    Conserved Domains (7) summary
    cd09550
    Location:947 → 1011
    SAM_EPH-A8; SAM domain of EPH-A8 subfamily of tyrosine kinase receptors
    smart00454
    Location:943 → 1010
    SAM; Sterile alpha motif
    cd00063
    Location:467 → 558
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:645 → 917
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam07714
    Location:650 → 913
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:577 → 645
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    cl02704
    Location:29 → 201
    EphR_LBD; Ligand Binding Domain of Ephrin Receptors

  3. XM_008410261.2 → XP_008408483.1  ephrin type-A receptor 8 isoform X2

    UniProtKB/TrEMBL
    A0A3P9Q3S1
    Conserved Domains (7) summary
    cd09550
    Location:953 → 1017
    SAM_EPH-A8; SAM domain of EPH-A8 subfamily of tyrosine kinase receptors
    smart00454
    Location:949 → 1016
    SAM; Sterile alpha motif
    cd00063
    Location:467 → 558
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:657 → 923
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam07714
    Location:662 → 919
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:575 → 657
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    cl02704
    Location:29 → 201
    EphR_LBD; Ligand Binding Domain of Ephrin Receptors

  4. XM_008410263.2 → XP_008408485.1  ephrin type-A receptor 8 isoform X4

    UniProtKB/TrEMBL
    A0A3P9Q3S2
    Related
    ENSPREP00000028493.1, ENSPRET00000028805.1
    Conserved Domains (7) summary
    cd09550
    Location:941 → 1005
    SAM_EPH-A8; SAM domain of EPH-A8 subfamily of tyrosine kinase receptors
    smart00454
    Location:937 → 1004
    SAM; Sterile alpha motif
    cd00063
    Location:467 → 558
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    cd05066
    Location:645 → 911
    PTKc_EphR_A; Catalytic domain of the Protein Tyrosine Kinases, Class EphA Ephrin Receptors
    pfam07714
    Location:650 → 907
    Pkinase_Tyr; Protein tyrosine kinase
    pfam14575
    Location:577 → 645
    EphA2_TM; Ephrin type-A receptor 2 transmembrane domain
    cl02704
    Location:29 → 201
    EphR_LBD; Ligand Binding Domain of Ephrin Receptors
Nucleotide Protein
Heading Accession and Version

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