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usp7 ubiquitin specific peptidase 7 (herpes virus-associated) [ Cynoglossus semilaevis (tongue sole) ]

Gene ID: 103393241, updated on 11-Mar-2024

Summary

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Gene symbol
usp7
Gene description
ubiquitin specific peptidase 7 (herpes virus-associated)
See related
Ensembl:ENSCSEG00000018615
Gene type
protein coding
RefSeq status
MODEL
Organism
Cynoglossus semilaevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae; Cynoglossinae; Cynoglossus
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: 17
Exon count:
31
Annotation release Status Assembly Chr Location
102 current Cse_v1.0 (GCF_000523025.1) 17 NC_024323.1 (11431974..11449099, complement)

Chromosome 17 - NC_024323.1Genomic Context describing neighboring genes Neighboring gene solute carrier family 2 member 6 Neighboring gene Lipopolysaccharide-induced tumor necrosis factor-alpha factor homolog-like Neighboring gene HUWE1 associated protein modifying stress responses a Neighboring gene dynactin 5 Neighboring gene NADH:ubiquinone oxidoreductase subunit AB1b

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_024323.1 Chromosome 17 Reference Cse_v1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cysteine-type deubiquitinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cysteine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein deubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of protein stability IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
ubiquitin carboxyl-terminal hydrolase 7

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cynoglossus semilaevis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Cse_v1.0 Primary Assembly

Genomic

  1. NC_024323.1 Reference Cse_v1.0 Primary Assembly

    Range
    11431974..11449099 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_008330133.3 → XP_008328355.1  ubiquitin carboxyl-terminal hydrolase 7

    UniProtKB/TrEMBL
    A0A3P8WRH4
    Related
    ENSCSEP00000029092.1, ENSCSET00000029493.1
    Conserved Domains (5) summary
    COG5077
    Location:28 → 1108
    COG5077; Ubiquitin carboxyl-terminal hydrolase [Posttranslational modification, protein turnover, chaperones]
    cd02659
    Location:218 → 529
    peptidase_C19C; A subfamily of Peptidase C19. Peptidase C19 contains ubiquitinyl hydrolases. They are intracellular peptidases that remove ubiquitin molecules from polyubiquinated peptides by cleavage of isopeptide bonds. They hydrolyze bonds involving the carboxyl ...
    cd03772
    Location:73 → 208
    MATH_HAUSP; Herpesvirus-associated ubiquitin-specific protease (HAUSP, also known as USP7) family, N-terminal MATH (TRAF-like) domain; composed of proteins similar to human HAUSP, an enzyme that specifically catalyzes the deubiquitylation of p53 and MDM2, hence ...
    pfam12436
    Location:626 → 873
    USP7_ICP0_bdg; ICP0-binding domain of Ubiquitin-specific protease 7
    pfam14533
    Location:883 → 1094
    USP7_C2; Ubiquitin-specific protease C-terminal
Nucleotide Protein
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