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brca2 BRCA2 DNA repair associated [ Cynoglossus semilaevis (tongue sole) ]

Gene ID: 103378186, updated on 11-Mar-2024

Summary

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Gene symbol
brca2
Gene description
BRCA2 DNA repair associated
Gene type
protein coding
RefSeq status
MODEL
Organism
Cynoglossus semilaevis
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Actinopterygii; Neopterygii; Teleostei; Neoteleostei; Acanthomorphata; Carangaria; Pleuronectiformes; Pleuronectoidei; Cynoglossidae; Cynoglossinae; Cynoglossus
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: 4
Exon count:
29
Annotation release Status Assembly Chr Location
102 current Cse_v1.0 (GCF_000523025.1) 4 NC_024310.1 (13216287..13228956, complement)

Chromosome 4 - NC_024310.1Genomic Context describing neighboring genes Neighboring gene tRNA methyltransferase 9B Neighboring gene NEDD4 binding protein 2-like 2 Neighboring gene furry homolog a (Drosophila) Neighboring gene extracellular calcium-sensing receptor-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_024310.1 Chromosome 4 Reference Cse_v1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in double-strand break repair via homologous recombination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of DNA-templated transcription IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
breast cancer type 2 susceptibility protein
Names
breast cancer 2, early onset

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Cynoglossus semilaevis Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Cse_v1.0 Primary Assembly

Genomic

  1. NC_024310.1 Reference Cse_v1.0 Primary Assembly

    Range
    13216287..13228956 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_025055232.1 → XP_024911000.1  breast cancer type 2 susceptibility protein

    Conserved Domains (5) summary
    cd04494
    Location:2047 → 2295
    BRCA2DBD_OB2; A subfamily of OB folds corresponding to the second OB fold (OB2) of the 800-amino acid C-terminal ssDNA binding domain (DBD) of BRCA2 (breast cancer susceptibility gene 2) protein, called BRCA2DBD. BRCA2 participates in homologous recombination-mediated ...
    pfam00634
    Location:1336 → 1363
    BRCA2; BRCA2 repeat
    pfam09103
    Location:1908 → 2036
    BRCA-2_OB1; BRCA2, oligonucleotide/oligosaccharide-binding, domain 1
    pfam09104
    Location:2295 → 2429
    BRCA-2_OB3; BRCA2, oligonucleotide/oligosaccharide-binding, domain 3
    pfam09169
    Location:1718 → 1904
    BRCA-2_helical; BRCA2, helical
Nucleotide Protein
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