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IL6ST interleukin 6 cytokine family signal transducer [ Chlorocebus sabaeus (green monkey) ]

Gene ID: 103221611, updated on 11-Mar-2024

Summary

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Gene symbol
IL6ST
Gene description
interleukin 6 cytokine family signal transducer
See related
Ensembl:ENSCSAG00000016226
Gene type
protein coding
RefSeq status
MODEL
Organism
Chlorocebus sabaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Cercopithecidae; Cercopithecinae; Chlorocebus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
18
Annotation release Status Assembly Chr Location
102 current Vero_WHO_p1.0 (GCF_015252025.1) Unplaced Scaffold NW_023666049.1 (1050897..1108503, complement)
100 previous assembly Chlorocebus_sabeus 1.1 (GCF_000409795.2) 4 NC_023645.1 (52174893..52232475, complement)

NW_023666049.1Genomic Context describing neighboring genes Neighboring gene heterogeneous nuclear ribonucleoprotein H-like Neighboring gene interleukin 31 receptor A Neighboring gene 40S ribosomal protein S2-like Neighboring gene uncharacterized LOC119628305 Neighboring gene ankyrin repeat domain 55 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cytokine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables cytokine receptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cytokine-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of tyrosine phosphorylation of STAT protein IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of CRLF-CLCF1 complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in external side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of receptor complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
interleukin-6 receptor subunit beta
Names
interleukin 6 signal transducer

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Chlorocebus sabaeus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Vero_WHO_p1.0

Genomic

  1. NW_023666049.1 Reference Vero_WHO_p1.0

    Range
    1050897..1108503 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_038010401.1 → XP_037866329.1  interleukin-6 receptor subunit beta isoform X3

    Conserved Domains (1) summary
    smart00060
    Location:230 → 310
    FN3; Fibronectin type 3 domain

  2. XM_007972856.2 → XP_007971047.1  interleukin-6 receptor subunit beta isoform X1

    See identical proteins and their annotated locations for XP_007971047.1

    UniProtKB/TrEMBL
    A0A0D9RUK8
    Conserved Domains (4) summary
    smart00060
    Location:519 → 599
    FN3; Fibronectin type 3 domain
    cd00063
    Location:222 → 321
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam06328
    Location:26 → 112
    Lep_receptor_Ig; Ig-like C2-type domain
    cl21522
    Location:129 → 216
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...

  3. XM_038010399.1 → XP_037866327.1  interleukin-6 receptor subunit beta isoform X2

    UniProtKB/TrEMBL
    A0A0D9RUK8
    Conserved Domains (4) summary
    smart00060
    Location:465 → 545
    FN3; Fibronectin type 3 domain
    cd00063
    Location:168 → 267
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
    pfam06328
    Location:1 → 58
    Lep_receptor_Ig; Ig-like C2-type domain
    cl21522
    Location:77 → 162
    FN3; Fibronectin type 3 domain; One of three types of internal repeats found in the plasma protein fibronectin. Its tenth fibronectin type III repeat contains an RGD cell recognition sequence in a flexible loop between 2 strands. Approximately 2% of all ...
Nucleotide Protein
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