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WNK2 WNK lysine deficient protein kinase 2 [ Orycteropus afer afer ]

Gene ID: 103207420, updated on 11-Mar-2024

Summary

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Gene symbol
WNK2
Gene description
WNK lysine deficient protein kinase 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Orycteropus afer afer (sub-species: afer)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Tubulidentata; Orycteropodidae; Orycteropus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
28
Annotation release Status Assembly Chr Location
101 current OryAfe1.0 (GCF_000298275.1) Unplaced Scaffold NW_006921955.1 (2993114..3372837)

NW_006921955.1Genomic Context describing neighboring genes Neighboring gene caspase recruitment domain family member 19 Neighboring gene ninjurin 1 Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_006921955 Unplaced Scaffold Reference OryAfe1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables chloride channel inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables potassium channel inhibitor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in monoatomic ion homeostasis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of sodium ion transport IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of potassium ion import across plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of sodium ion transmembrane transporter activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase WNK2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Orycteropus afer afer Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference OryAfe1.0 Primary Assembly

Genomic

  1. NW_006921955.1 Reference OryAfe1.0 Primary Assembly

    Range
    2993114..3372837
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007953023.1 → XP_007951214.1  serine/threonine-protein kinase WNK2

    UniProtKB/TrEMBL
    A0A8B7AUB4
    Conserved Domains (3) summary
    smart00220
    Location:202 → 455
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14032
    Location:195 → 460
    STKc_WNK2_like; Catalytic domain of With No Lysine (WNK) 2-like Serine/Threonine kinases
    pfam12202
    Location:476 → 513
    OSR1_C; Oxidative-stress-responsive kinase 1 C terminal
Nucleotide Protein
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