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NHERF4 NHERF family PDZ scaffold protein 4 [ Orycteropus afer afer ]

Gene ID: 103193276, updated on 11-Mar-2024

Summary

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Gene symbol
NHERF4
Gene description
NHERF family PDZ scaffold protein 4
Gene type
protein coding
RefSeq status
MODEL
Organism
Orycteropus afer afer (sub-species: afer)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Tubulidentata; Orycteropodidae; Orycteropus
Also known as
PDZD3
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
11
Annotation release Status Assembly Chr Location
101 current OryAfe1.0 (GCF_000298275.1) Unplaced Scaffold NW_006921623.1 (1921328..1925203, complement)

NW_006921623.1Genomic Context describing neighboring genes Neighboring gene small nucleolar RNA SNORA61 Neighboring gene Cbl proto-oncogene Neighboring gene dynein regulatory complex subunit 12 homolog Neighboring gene NLR family member X1 Neighboring gene ATP binding cassette subfamily G member 4

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_006921623 Unplaced Scaffold Reference OryAfe1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables protein-membrane adaptor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in protein localization to plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in apical plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
Na(+)/H(+) exchange regulatory cofactor NHE-RF4
Names
PDZ domain containing 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Orycteropus afer afer Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference OryAfe1.0 Primary Assembly

Genomic

  1. NW_006921623.1 Reference OryAfe1.0 Primary Assembly

    Range
    1921328..1925203 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007936434.1 → XP_007934625.1  Na(+)/H(+) exchange regulatory cofactor NHE-RF4

    UniProtKB/TrEMBL
    A0A8B6ZG18
    Conserved Domains (2) summary
    smart00228
    Location:407 → 476
    PDZ; Domain present in PSD-95, Dlg, and ZO-1/2
    cd00992
    Location:47 → 127
    PDZ_signaling; PDZ domain found in a variety of Eumetazoan signaling molecules, often in tandem arrangements. May be responsible for specific protein-protein interactions, as most PDZ domains bind C-terminal polypeptides, and binding to internal (non-C-terminal) ...
Nucleotide Protein
Heading Accession and Version

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