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pik3c3 phosphatidylinositol 3-kinase, catalytic subunit type 3 [ Callorhinchus milii (elephant shark) ]

Gene ID: 103181014, updated on 11-Mar-2024

Summary

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Gene symbol
pik3c3
Gene description
phosphatidylinositol 3-kinase, catalytic subunit type 3
See related
Ensembl:ENSCMIG00000013036
Gene type
protein coding
RefSeq status
MODEL
Organism
Callorhinchus milii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Chondrichthyes; Holocephali; Chimaeriformes; Callorhinchidae; Callorhinchus
Orthologs
human zebrafish all
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Genomic context

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Location:
chromosome: Un
Exon count:
27
Annotation release Status Assembly Chr Location
101 current IMCB_Cmil_1.0 (GCF_018977255.1) Unplaced Scaffold NW_024704742.1 (128663599..128719082, complement)
100 previous assembly Callorhinchus_milii-6.1.3 (GCF_000165045.1) Unplaced Scaffold NW_006890105.1 (4357822..4411933)

NW_024704742.1Genomic Context describing neighboring genes Neighboring gene Ras-like without CAAX 1 Neighboring gene urea transporter 1-like Neighboring gene natriuretic peptide receptor 3 Neighboring gene atrial natriuretic peptide receptor 2

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Elephant shark genome provides unique insights into gnathostome evolution. Venkatesh B, et al. Nature, 2014 Jan 9. PMID 24402279, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in autophagosome assembly IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in autophagy of peroxisome IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in endocytosis IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endosome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in peroxisome IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in phagophore assembly site IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex, class III, type I IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex, class III, type II IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 3-kinase catalytic subunit type 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Callorhinchus milii Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference IMCB_Cmil_1.0 Primary Assembly

Genomic

  1. NW_024704742.1 Reference IMCB_Cmil_1.0 Primary Assembly

    Range
    128663599..128719082 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042335548.1 → XP_042191482.1  phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X4

    UniProtKB/TrEMBL
    A0A4W3IXR5
    Conserved Domains (3) summary
    cd08397
    Location:26 → 186
    C2_PI3K_class_III; C2 domain present in class III phosphatidylinositol 3-kinases (PI3Ks)
    cd00870
    Location:283 → 504
    PI3Ka_III; Phosphoinositide 3-kinase (PI3K) class III, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3Ks class III ...
    cd00896
    Location:540 → 884
    PI3Kc_III; Catalytic domain of Class III Phosphoinositide 3-kinase

  2. XM_042335544.1 → XP_042191478.1  phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X3

    UniProtKB/TrEMBL
    A0A4W3IXR5, V9KDS5
    Conserved Domains (3) summary
    cd08397
    Location:26 → 186
    C2_PI3K_class_III; C2 domain present in class III phosphatidylinositol 3-kinases (PI3Ks)
    cd00870
    Location:283 → 506
    PI3Ka_III; Phosphoinositide 3-kinase (PI3K) class III, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3Ks class III ...
    cd00896
    Location:542 → 886
    PI3Kc_III; Catalytic domain of Class III Phosphoinositide 3-kinase

  3. XM_042335538.1 → XP_042191472.1  phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X2

    UniProtKB/TrEMBL
    A0A4W3IXR5
    Conserved Domains (3) summary
    cd08397
    Location:26 → 195
    C2_PI3K_class_III; C2 domain present in class III phosphatidylinositol 3-kinases (PI3Ks)
    cd00870
    Location:292 → 513
    PI3Ka_III; Phosphoinositide 3-kinase (PI3K) class III, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3Ks class III ...
    cd00896
    Location:549 → 893
    PI3Kc_III; Catalytic domain of Class III Phosphoinositide 3-kinase

  4. XM_042335532.1 → XP_042191466.1  phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1

    UniProtKB/TrEMBL
    A0A4W3IXR5
    Conserved Domains (3) summary
    cd08397
    Location:26 → 195
    C2_PI3K_class_III; C2 domain present in class III phosphatidylinositol 3-kinases (PI3Ks)
    cd00870
    Location:292 → 515
    PI3Ka_III; Phosphoinositide 3-kinase (PI3K) class III, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3Ks class III ...
    cd00896
    Location:551 → 895
    PI3Kc_III; Catalytic domain of Class III Phosphoinositide 3-kinase

  5. XM_042335549.1 → XP_042191483.1  phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X5

    UniProtKB/TrEMBL
    A0A4W3IU88
    Conserved Domains (2) summary
    cd00870
    Location:97 → 320
    PI3Ka_III; Phosphoinositide 3-kinase (PI3K) class III, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3Ks class III ...
    cd00896
    Location:356 → 700
    PI3Kc_III; Catalytic domain of Class III Phosphoinositide 3-kinase
Nucleotide Protein
Heading Accession and Version

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