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PIK3C3 phosphatidylinositol 3-kinase catalytic subunit type 3 [ Erinaceus europaeus (western European hedgehog) ]

Gene ID: 103124329, updated on 11-Mar-2024

Summary

Gene symbol
PIK3C3
Gene description
phosphatidylinositol 3-kinase catalytic subunit type 3
Gene type
protein coding
RefSeq status
MODEL
Organism
Erinaceus europaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae; Erinaceus
Orthologs
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Genomic context

Location:
chromosome: 15
Exon count:
25
Annotation release Status Assembly Chr Location
RS_2023_10 current mEriEur2.1 (GCF_950295315.1) 15 NC_080176.1 (57098525..57232603)
101 previous assembly EriEur2.0 (GCF_000296755.1) Unplaced Scaffold NW_006804696.1 (609770..748913)

Chromosome 15 - NC_080176.1Genomic Context describing neighboring genes Neighboring gene snurportin-1-like Neighboring gene small ribosomal subunit protein eS10-like Neighboring gene Ras like without CAAX 2 Neighboring gene synaptotagmin 4

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in autophagosome assembly IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in autophagy of peroxisome IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in endocytosis IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in endosome IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in peroxisome IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in phagophore assembly site IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of phosphatidylinositol 3-kinase complex, class III, type I IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of phosphatidylinositol 3-kinase complex, class III, type II IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
phosphatidylinositol 3-kinase catalytic subunit type 3

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_950295315.1-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mEriEur2.1

Genomic

  1. NC_080176.1 Reference mEriEur2.1

    Range
    57098525..57232603
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_016193414.2XP_016048900.1  phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X1

    UniProtKB/TrEMBL
    A0A1S3WRD8
    Conserved Domains (3) summary
    cd08397
    Location:26186
    C2_PI3K_class_III; C2 domain present in class III phosphatidylinositol 3-kinases (PI3Ks)
    cd00870
    Location:283503
    PI3Ka_III; Phosphoinositide 3-kinase (PI3K) class III, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, PI3Ks class III ...
    cd00896
    Location:539883
    PI3Kc_III; Catalytic domain of Class III Phosphoinositide 3-kinase
  2. XM_060173799.1XP_060029782.1  phosphatidylinositol 3-kinase catalytic subunit type 3 isoform X2