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CHEK1 checkpoint kinase 1 [ Erinaceus europaeus (western European hedgehog) ]

Gene ID: 103111367, updated on 11-Mar-2024

Summary

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Gene symbol
CHEK1
Gene description
checkpoint kinase 1
Gene type
protein coding
RefSeq status
MODEL
Organism
Erinaceus europaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae; Erinaceus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 20
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2023_10 current mEriEur2.1 (GCF_950295315.1) 20 NC_080181.1 (9035064..9056361, complement)
101 previous assembly EriEur2.0 (GCF_000296755.1) Unplaced Scaffold NW_006804052.1 (3152394..3172720, complement)

Chromosome 20 - NC_080181.1Genomic Context describing neighboring genes Neighboring gene protein PIP-1-like Neighboring gene acrosomal protein SP-10 Neighboring gene STT3 oligosaccharyltransferase complex catalytic subunit A Neighboring gene EI24 autophagy associated transmembrane protein

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in mitotic G2 DNA damage checkpoint signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in site of double-strand break IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
serine/threonine-protein kinase Chk1

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_950295315.1-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mEriEur2.1

Genomic

  1. NC_080181.1 Reference mEriEur2.1

    Range
    9035064..9056361 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_060179780.1 → XP_060035763.1  serine/threonine-protein kinase Chk1 isoform X2

  2. XM_007520645.3 → XP_007520707.1  serine/threonine-protein kinase Chk1 isoform X1

    UniProtKB/TrEMBL
    A0A1S2ZKC6, A0A1S2ZKD6
    Conserved Domains (2) summary
    smart00220
    Location:9 → 264
    S_TKc; Serine/Threonine protein kinases, catalytic domain
    cd14069
    Location:7 → 265
    STKc_Chk1; Catalytic domain of the Serine/Threonine kinase, Checkpoint kinase 1
Nucleotide Protein
Heading Accession and Version

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