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DTX4 deltex E3 ubiquitin ligase 4 [ Erinaceus europaeus (western European hedgehog) ]

Gene ID: 103110318, updated on 11-Mar-2024

Summary

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Gene symbol
DTX4
Gene description
deltex E3 ubiquitin ligase 4
Gene type
protein coding
RefSeq status
MODEL
Organism
Erinaceus europaeus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Eulipotyphla; Erinaceidae; Erinaceinae; Erinaceus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 17
Exon count:
9
Annotation release Status Assembly Chr Location
RS_2023_10 current mEriEur2.1 (GCF_950295315.1) 17 NC_080178.1 (8528770..8588111)
101 previous assembly EriEur2.0 (GCF_000296755.1) Unplaced Scaffold NW_006804027.1 (2806035..2864767)

Chromosome 17 - NC_080178.1Genomic Context describing neighboring genes Neighboring gene glycine-N-acyltransferase like 2 Neighboring gene FAM111 trypsin like peptidase B Neighboring gene FAM111 trypsin like peptidase A Neighboring gene U6atac minor spliceosomal RNA Neighboring gene macrophage expressed 1 Neighboring gene olfactory receptor 5A1-like

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in Notch signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase DTX4

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_950295315.1-RS_2023_10

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mEriEur2.1

Genomic

  1. NC_080178.1 Reference mEriEur2.1

    Range
    8528770..8588111
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007519492.3 → XP_007519554.1  E3 ubiquitin-protein ligase DTX4

    UniProtKB/TrEMBL
    A0A1S2ZHQ8
    Conserved Domains (4) summary
    smart00678
    Location:8 → 86
    WWE; Domain in Deltex and TRIP12 homologues. Possibly involved in regulation of ubiquitin-mediated proteolysis
    cd09633
    Location:472 → 604
    Deltex_C; Domain found at the C-terminus of deltex-like
    cd00162
    Location:404 → 465
    RING; RING-finger (Really Interesting New Gene) domain, a specialized type of Zn-finger of 40 to 60 residues that binds two atoms of zinc; defined by the 'cross-brace' motif C-X2-C-X(9-39)-C-X(1-3)- H-X(2-3)-(N/C/H)-X2-C-X(4-48)C-X2-C; probably involved in ...
    pfam02825
    Location:90 → 144
    WWE; WWE domain
Nucleotide Protein
Heading Accession and Version

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