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EP300 E1A binding protein p300 [ Lipotes vexillifer (Yangtze River dolphin) ]

Gene ID: 103079020, updated on 11-Mar-2024

Summary

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Gene symbol
EP300
Gene description
E1A binding protein p300
Gene type
protein coding
RefSeq status
MODEL
Organism
Lipotes vexillifer
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Lipotidae; Lipotes
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
31
Annotation release Status Assembly Chr Location
100 current Lipotes_vexillifer_v1 (GCF_000442215.1) Unplaced Scaffold NW_006780611.1 (7943048..8016183, complement)

NW_006780611.1Genomic Context describing neighboring genes Neighboring gene L3MBTL histone methyl-lysine binding protein 2 Neighboring gene glycine cleavage system H protein, mitochondrial-like Neighboring gene heat-responsive protein 12 pseudogene Neighboring gene ring-box 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_006780611 unplaced scaffold reference Lipotes_vexillifer_v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables chromatin DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables histone acetyltransferase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription coactivator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in positive regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
part_of histone acetyltransferase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of transcription regulator complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
histone acetyltransferase p300

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Lipotes vexillifer Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Lipotes_vexillifer_v1 Primary Assembly

Genomic

  1. NW_006780611.1 Reference Lipotes_vexillifer_v1 Primary Assembly

    Range
    7943048..8016183 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007453979.1 → XP_007454041.1  histone acetyltransferase p300

    UniProtKB/TrEMBL
    A0A340WY96
    Conserved Domains (11) summary
    cd05495
    Location:1052 → 1159
    Bromo_cbp_like; Bromodomain, cbp_like subfamily. Cbp (CREB binding protein or CREBBP) is an acetyltransferase acting on histone, which gives a specific tag for transcriptional activation and also acetylates non-histone proteins. CREBBP binds specifically to ...
    smart00551
    Location:1730 → 1808
    ZnF_TAZ; TAZ zinc finger, present in p300 and CBP
    cd02337
    Location:1669 → 1709
    ZZ_CBP; Zinc finger, ZZ type. Zinc finger present in CBP/p300 and related proteins. The ZZ motif coordinates two zinc ions and most likely participates in ligand binding or molecular scaffolding. CREB-binding protein (CBP) is a large multidomain protein that ...
    pfam08430
    Location:119 → 217
    Forkhead_N; Forkhead N-terminal region
    pfam09606
    Location:1938 → 2418
    Med15; ARC105 or Med15 subunit of Mediator complex non-fungal
    cd15802
    Location:1171 → 1243
    RING_CBP-p300; atypical RING domain found in CREB-binding protein and p300 histone acetyltransferases
    cd15646
    Location:1244 → 1278
    PHD_p300; PHD finger found in histone acetyltransferase p300
    pfam02135
    Location:348 → 415
    zf-TAZ; TAZ zinc finger
    pfam02172
    Location:567 → 647
    KIX; KIX domain
    pfam08214
    Location:1307 → 1613
    HAT_KAT11; Histone acetylation protein
    pfam09030
    Location:2008 → 2096
    Creb_binding; Creb binding
Nucleotide Protein
Heading Accession and Version

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