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MITF melanocyte inducing transcription factor [ Lipotes vexillifer (Yangtze River dolphin) ]

Gene ID: 103074364, updated on 11-Mar-2024

Summary

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Gene symbol
MITF
Gene description
melanocyte inducing transcription factor
Gene type
protein coding
RefSeq status
MODEL
Organism
Lipotes vexillifer
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Lipotidae; Lipotes
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
15
Annotation release Status Assembly Chr Location
100 current Lipotes_vexillifer_v1 (GCF_000442215.1) Unplaced Scaffold NW_006772616.1 (1018563..1241131)

NW_006772616.1Genomic Context describing neighboring genes Neighboring gene cytochrome c-like Neighboring gene WASH complex subunit CCDC53-like Neighboring gene forkhead box P1 Neighboring gene eukaryotic translation initiation factor 4E family member 3 Neighboring gene G protein-coupled receptor 27

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_006772616 unplaced scaffold reference Lipotes_vexillifer_v1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables DNA-binding transcription factor activity, RNA polymerase II-specific IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables RNA polymerase II cis-regulatory region sequence-specific DNA binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein dimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in melanocyte differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of transcription by RNA polymerase II IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
microphthalmia-associated transcription factor
Names
melanogenesis associated transcription factor

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Lipotes vexillifer Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Lipotes_vexillifer_v1 Primary Assembly

Genomic

  1. NW_006772616.1 Reference Lipotes_vexillifer_v1 Primary Assembly

    Range
    1018563..1241131
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007447650.1 → XP_007447712.1  microphthalmia-associated transcription factor

    UniProtKB/TrEMBL
    A0A340WJG5
    Conserved Domains (3) summary
    cd00083
    Location:303 → 363
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam11851
    Location:391 → 504
    DUF3371; Domain of unknown function (DUF3371)
    pfam15951
    Location:56 → 194
    MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus

  2. XM_007447655.1 → XP_007447717.1  microphthalmia-associated transcription factor

    See identical proteins and their annotated locations for XP_007447717.1

    UniProtKB/TrEMBL
    A0A340WGD9
    Conserved Domains (2) summary
    cd00083
    Location:101 → 161
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam11851
    Location:189 → 302
    DUF3371; Domain of unknown function (DUF3371)

  3. XM_007447651.1 → XP_007447713.1  microphthalmia-associated transcription factor

    UniProtKB/TrEMBL
    A0A340WDQ6
    Conserved Domains (3) summary
    cd00083
    Location:287 → 347
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam11851
    Location:375 → 488
    DUF3371; Domain of unknown function (DUF3371)
    pfam15951
    Location:40 → 178
    MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus

  4. XM_007447656.1 → XP_007447718.1  microphthalmia-associated transcription factor

    UniProtKB/TrEMBL
    A0A340WDR3
    Conserved Domains (3) summary
    cd00083
    Location:251 → 311
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam11851
    Location:339 → 452
    DUF3371; Domain of unknown function (DUF3371)
    pfam15951
    Location:4 → 142
    MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus

  5. XM_007447654.1 → XP_007447716.1  microphthalmia-associated transcription factor

    See identical proteins and their annotated locations for XP_007447716.1

    UniProtKB/TrEMBL
    A0A340WGD9
    Conserved Domains (2) summary
    cd00083
    Location:101 → 161
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam11851
    Location:189 → 302
    DUF3371; Domain of unknown function (DUF3371)

  6. XM_007447652.1 → XP_007447714.1  microphthalmia-associated transcription factor

    UniProtKB/TrEMBL
    A0A340WKU2
    Conserved Domains (3) summary
    cd00083
    Location:202 → 262
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam11851
    Location:290 → 403
    DUF3371; Domain of unknown function (DUF3371)
    pfam15951
    Location:11 → 87
    MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus

  7. XM_007447653.1 → XP_007447715.1  microphthalmia-associated transcription factor

    UniProtKB/TrEMBL
    A0A340WL13
    Conserved Domains (3) summary
    cd00083
    Location:196 → 256
    HLH; Helix-loop-helix domain, found in specific DNA- binding proteins that act as transcription factors; 60-100 amino acids long. A DNA-binding basic region is followed by two alpha-helices separated by a variable loop region; HLH forms homo- and heterodimers, ...
    pfam11851
    Location:284 → 397
    DUF3371; Domain of unknown function (DUF3371)
    pfam15951
    Location:11 → 87
    MITF_TFEB_C_3_N; MITF/TFEB/TFEC/TFE3 N-terminus
Nucleotide Protein
Heading Accession and Version

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