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LCK LCK proto-oncogene, Src family tyrosine kinase [ Python bivittatus (Burmese python) ]

Gene ID: 103065569, updated on 11-Apr-2024

Summary

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Gene symbol
LCK
Gene description
LCK proto-oncogene, Src family tyrosine kinase
Gene type
protein coding
RefSeq status
MODEL
Organism
Python bivittatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Henophidia; Pythonidae; Python
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
13
Annotation release Status Assembly Chr Location
102 current Python_molurus_bivittatus-5.0.2 (GCF_000186305.1) Unplaced Scaffold NW_006533835.1 (172131..209786)

NW_006533835.1Genomic Context describing neighboring genes Neighboring gene myotubularin-related protein 9-like Neighboring gene family with sequence similarity 167 member B Neighboring gene histone deacetylase 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_006533835 Unplaced Scaffold Reference Python_molurus_bivittatus-5.0.2 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ATP binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables non-membrane spanning protein tyrosine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables signaling receptor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in B cell receptor signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in T cell differentiation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cell surface receptor protein tyrosine kinase signaling pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in innate immune response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extrinsic component of cytoplasmic side of plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
tyrosine-protein kinase Lck

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Python bivittatus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Python_molurus_bivittatus-5.0.2 Primary Assembly

Genomic

  1. NW_006533835.1 Reference Python_molurus_bivittatus-5.0.2 Primary Assembly

    Range
    172131..209786
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007431958.3 → XP_007432020.1  tyrosine-protein kinase Lck

    UniProtKB/TrEMBL
    A0A9F2QZZ6
    Conserved Domains (4) summary
    cd10362
    Location:122 → 222
    SH2_Src_Lck; Src homology 2 (SH2) domain in lymphocyte cell kinase (Lck)
    cd05067
    Location:236 → 499
    PTKc_Lck_Blk; Catalytic domain of the Protein Tyrosine Kinases, Lymphocyte-specific kinase and Blk
    pfam07714
    Location:244 → 493
    Pkinase_Tyr; Protein tyrosine kinase
    cl17036
    Location:64 → 117
    SH3; Src Homology 3 domain superfamily
Nucleotide Protein
Heading Accession and Version

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