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SESN2 sestrin 2 [ Python bivittatus (Burmese python) ]

Gene ID: 103051203, updated on 11-Apr-2024

Summary

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Gene symbol
SESN2
Gene description
sestrin 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Python bivittatus
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Lepidosauria; Squamata; Bifurcata; Unidentata; Episquamata; Toxicofera; Serpentes; Henophidia; Pythonidae; Python
Orthologs
human mouse all
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Genomic context

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See SESN2 in Genome Data Viewer
Location:
chromosome: Un
Exon count:
10
Annotation release Status Assembly Chr Location
102 current Python_molurus_bivittatus-5.0.2 (GCF_000186305.1) Unplaced Scaffold NW_006536189.1 (77335..113913, complement)

NW_006536189.1Genomic Context describing neighboring genes Neighboring gene phosphatase and actin regulator 4 Neighboring gene mediator complex subunit 18

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_006536189 Unplaced Scaffold Reference Python_molurus_bivittatus-5.0.2 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables L-leucine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity, acting on peroxide as acceptor IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cellular response to L-leucine IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in cellular response to leucine starvation IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in negative regulation of TORC1 signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of macroautophagy IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of response to reactive oxygen species IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
sestrin-2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Python bivittatus Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference Python_molurus_bivittatus-5.0.2 Primary Assembly

Genomic

  1. NW_006536189.1 Reference Python_molurus_bivittatus-5.0.2 Primary Assembly

    Range
    77335..113913 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007438412.3 → XP_007438474.2  sestrin-2 isoform X2

    UniProtKB/TrEMBL
    A0A9F2R790
    Conserved Domains (1) summary
    pfam04636
    Location:74 → 509
    PA26; PA26 p53-induced protein (sestrin)

  2. XM_007438411.3 → XP_007438473.2  sestrin-2 isoform X1

    UniProtKB/TrEMBL
    A0A9F2WJT0
    Conserved Domains (1) summary
    pfam04636
    Location:74 → 510
    PA26; PA26 p53-induced protein (sestrin)
Nucleotide Protein
Heading Accession and Version

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