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SHMT2 serine hydroxymethyltransferase 2 [ Balaenoptera acutorostrata (minke whale) ]

Gene ID: 103013352, updated on 11-Mar-2024

Summary

Gene symbol
SHMT2
Gene description
serine hydroxymethyltransferase 2
Gene type
protein coding
RefSeq status
MODEL
Organism
Balaenoptera acutorostrata
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Mysticeti; Balaenopteridae; Balaenoptera
Orthologs
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Genomic context

Location:
chromosome: 11
Exon count:
13
Annotation release Status Assembly Chr Location
RS_2023_06 current mBalAcu1.1 (GCF_949987535.1) 11 NC_080074.1 (59823397..59828358, complement)
101 previous assembly BalAcu1.0 (GCF_000493695.1) Unplaced Scaffold NW_006726687.1 (10452003..10457112)

Chromosome 11 - NC_080074.1Genomic Context describing neighboring genes Neighboring gene SH3 and cysteine rich domain 3 Neighboring gene NDUFA4 mitochondrial complex associated like 2 Neighboring gene neurexophilin 4 Neighboring gene LDL receptor related protein 1

Genomic regions, transcripts, and products

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables cobalt ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables glycine hydroxymethyltransferase activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables mRNA 5'-UTR binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables mRNA regulatory element binding translation repressor activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
PubMed 
enables pyridoxal phosphate binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables serine binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables zinc ion binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in L-serine catabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in folic acid metabolic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in glycine biosynthetic process from serine IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in protein homotetramerization IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in purine nucleobase biosynthetic process IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in regulation of oxidative phosphorylation IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in response to type I interferon IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in tetrahydrofolate interconversion IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
part_of BRISC complex IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in cytosol IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in mitochondrial inner membrane IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in mitochondrial matrix IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
serine hydroxymethyltransferase, mitochondrial

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_949987535.1-RS_2023_06

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference mBalAcu1.1

Genomic

  1. NC_080074.1 Reference mBalAcu1.1

    Range
    59823397..59828358 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_007198683.3XP_007198745.2  serine hydroxymethyltransferase, mitochondrial isoform X2

  2. XM_057556995.1XP_057412978.1  serine hydroxymethyltransferase, mitochondrial isoform X3

  3. XM_057556994.1XP_057412977.1  serine hydroxymethyltransferase, mitochondrial isoform X1