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CENPF centromere protein F [ Physeter catodon (sperm whale) ]

Gene ID: 102993182, updated on 10-Mar-2024

Summary

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Gene symbol
CENPF
Gene description
centromere protein F
See related
Ensembl:ENSPCTG00005003467
Gene type
protein coding
RefSeq status
MODEL
Organism
Physeter catodon
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Artiodactyla; Whippomorpha; Cetacea; Odontoceti; Physeteridae; Physeter
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 4
Exon count:
21
Annotation release Status Assembly Chr Location
RS_2023_04 current ASM283717v5 (GCF_002837175.3) 4 NC_041217.1 (31305039..31366177, complement)
102 previous assembly ASM283717v2 (GCF_002837175.2) 4 NC_041217.1 (31305060..31366179, complement)

Chromosome 4 - NC_041217.1Genomic Context describing neighboring genes Neighboring gene potassium two pore domain channel subfamily K member 2 Neighboring gene solute carrier family 52, riboflavin transporter, member 2-like Neighboring gene protein tyrosine phosphatase non-receptor type 14 Neighboring gene uncharacterized LOC114486140

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables dynein complex binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables microtubule binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein homodimerization activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables transcription factor binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in metaphase chromosome alignment IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in regulation of G2/M transition of mitotic cell cycle IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in chromosome, centromeric region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in nucleus IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in spindle pole IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
centromere protein F

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: GCF_002837175.3-RS_2023_04

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ASM283717v5 Primary Assembly

Genomic

  1. NC_041217.1 Reference ASM283717v5 Primary Assembly

    Range
    31305039..31366177 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_024133899.3 → XP_023989667.1  centromere protein F isoform X1

    UniProtKB/TrEMBL
    A0A2Y9THF5
    Related
    ENSPCTP00005004894.1, ENSPCTT00005005381.1
    Conserved Domains (5) summary
    pfam10473
    Location:2094 → 2233
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam10481
    Location:1 → 307
    CENP-F_N; Cenp-F N-terminal domain
    pfam10490
    Location:2930 → 2976
    CENP-F_C_Rb_bdg; Rb-binding domain of kinetochore protein Cenp-F/LEK1
    cl25574
    Location:2662 → 3073
    TOP2c; TopoisomeraseII
    cl25732
    Location:1948 → 2737
    SMC_N; RecF/RecN/SMC N terminal domain

  2. XM_024133901.3 → XP_023989669.1  centromere protein F isoform X2

    UniProtKB/TrEMBL
    A0A2Y9TKL7
    Related
    ENSPCTP00005004918.1, ENSPCTT00005005408.1
    Conserved Domains (5) summary
    pfam10473
    Location:2094 → 2233
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam10481
    Location:1 → 307
    CENP-F_N; Cenp-F N-terminal domain
    pfam10490
    Location:2879 → 2925
    CENP-F_C_Rb_bdg; Rb-binding domain of kinetochore protein Cenp-F/LEK1
    cl25574
    Location:2611 → 3022
    TOP2c; TopoisomeraseII
    cl25732
    Location:1875 → 2723
    SMC_N; RecF/RecN/SMC N terminal domain

  3. XM_024133900.2 → XP_023989668.1  centromere protein F isoform X1

    UniProtKB/TrEMBL
    A0A2Y9THF5
    Conserved Domains (5) summary
    pfam10473
    Location:2094 → 2233
    CENP-F_leu_zip; Leucine-rich repeats of kinetochore protein Cenp-F/LEK1
    pfam10481
    Location:1 → 307
    CENP-F_N; Cenp-F N-terminal domain
    pfam10490
    Location:2930 → 2976
    CENP-F_C_Rb_bdg; Rb-binding domain of kinetochore protein Cenp-F/LEK1
    cl25574
    Location:2662 → 3073
    TOP2c; TopoisomeraseII
    cl25732
    Location:1948 → 2737
    SMC_N; RecF/RecN/SMC N terminal domain
Nucleotide Protein
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