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ITGB2 integrin subunit beta 2 [ Panthera tigris (tiger) ]

Gene ID: 102962262, updated on 10-Mar-2024

Summary

Gene symbol
ITGB2
Gene description
integrin subunit beta 2
See related
Ensembl:ENSPTIG00000021415
Gene type
protein coding
RefSeq status
MODEL
Organism
Panthera tigris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Pantherinae; Panthera
Orthologs
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Genomic context

Location:
chromosome: C2
Exon count:
16
Annotation release Status Assembly Chr Location
102 current P.tigris_Pti1_mat1.1 (GCF_018350195.1) C2 NC_056668.1 (1717003..1741750)

Chromosome C2 - NC_056668.1Genomic Context describing neighboring genes Neighboring gene SLX9 ribosome biogenesis factor Neighboring gene uncharacterized LOC122230667 Neighboring gene PTTG1 interacting protein Neighboring gene small ubiquitin like modifier 3

Genomic regions, transcripts, and products

Genomic Sequence:
NC_056668.1 Chromosome C2 Reference P.tigris_Pti1_mat1.1 Primary Assembly

General gene information

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables amyloid-beta binding IEA
Inferred from Electronic Annotation
more info
PubMed 
enables integrin binding IEA
Inferred from Electronic Annotation
more info
PubMed 
Process Evidence Code Pubs
involved_in cell adhesion mediated by integrin IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in cell-matrix adhesion IEA
Inferred from Electronic Annotation
more info
PubMed 
involved_in integrin-mediated signaling pathway IEA
Inferred from Electronic Annotation
more info
PubMed 
Component Evidence Code Pubs
located_in cell surface IEA
Inferred from Electronic Annotation
more info
PubMed 
located_in focal adhesion IEA
Inferred from Electronic Annotation
more info
PubMed 
part_of integrin complex IEA
Inferred from Electronic Annotation
more info
PubMed 

General protein information

Preferred Names
integrin beta-2
Names
integrin, beta 2 (complement component 3 receptor 3 and 4 subunit)

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Panthera tigris Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference P.tigris_Pti1_mat1.1 Primary Assembly

Genomic

  1. NC_056668.1 Reference P.tigris_Pti1_mat1.1 Primary Assembly

    Range
    1717003..1741750
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042998936.1XP_042854870.1  integrin beta-2

    UniProtKB/TrEMBL
    A0A8C9KQW5
    Conserved Domains (1) summary
    smart00187
    Location:33447
    INB; Integrin beta subunits (N-terminal portion of extracellular region)