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AMFR autocrine motility factor receptor [ Panthera tigris (tiger) ]

Gene ID: 102959972, updated on 10-Mar-2024

Summary

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Gene symbol
AMFR
Gene description
autocrine motility factor receptor
See related
Ensembl:ENSPTIG00000019995
Gene type
protein coding
RefSeq status
MODEL
Organism
Panthera tigris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Pantherinae; Panthera
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: E2
Exon count:
17
Annotation release Status Assembly Chr Location
102 current P.tigris_Pti1_mat1.1 (GCF_018350195.1) E2 NC_056674.1 (33382200..33426263, complement)

Chromosome E2 - NC_056674.1Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC122234307 Neighboring gene G protein subunit alpha o1 Neighboring gene uncharacterized LOC122234306 Neighboring gene nudix hydrolase 21 Neighboring gene 2-oxoglutarate and iron dependent oxygenase domain containing 1

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056674.1 Chromosome E2 Reference P.tigris_Pti1_mat1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables ubiquitin binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables ubiquitin protein ligase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in endoplasmic reticulum unfolded protein response IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein K48-linked ubiquitination IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in ubiquitin-dependent protein catabolic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytosol IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in endoplasmic reticulum IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of ubiquitin ligase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
E3 ubiquitin-protein ligase AMFR

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Panthera tigris Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference P.tigris_Pti1_mat1.1 Primary Assembly

Genomic

  1. NC_056674.1 Reference P.tigris_Pti1_mat1.1 Primary Assembly

    Range
    33382200..33426263 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042968523.1 → XP_042824457.1  E3 ubiquitin-protein ligase AMFR isoform X1

    UniProtKB/TrEMBL
    A0A8C9KLG5
    Conserved Domains (4) summary
    COG5243
    Location:86 → 382
    HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
    cd14421
    Location:458 → 498
    CUE_AMFR; CUE domain found in autocrine motility factor receptor (AMFR) and similar proteins
    cd16455
    Location:339 → 382
    RING-H2_AMFR; RING finger, H2 subclass, found in autocrine motility factor receptor (AMFR) and similar proteins
    pfam18442
    Location:575 → 600
    G2BR; E3 gp78 Ube2g2-binding region (G2BR)

  2. XM_042968525.1 → XP_042824459.1  E3 ubiquitin-protein ligase AMFR isoform X3

    UniProtKB/TrEMBL
    A0A8C9KLG5
    Conserved Domains (4) summary
    COG5243
    Location:2 → 287
    HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
    cd14421
    Location:363 → 403
    CUE_AMFR; CUE domain found in autocrine motility factor receptor (AMFR) and similar proteins
    cd16455
    Location:244 → 287
    RING-H2_AMFR; RING finger, H2 subclass, found in autocrine motility factor receptor (AMFR) and similar proteins
    pfam18442
    Location:480 → 505
    G2BR; E3 gp78 Ube2g2-binding region (G2BR)

  3. XM_042968524.1 → XP_042824458.1  E3 ubiquitin-protein ligase AMFR isoform X2

    UniProtKB/TrEMBL
    A0A8C9KLG5
    Conserved Domains (4) summary
    COG5243
    Location:86 → 382
    HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
    cd14421
    Location:458 → 498
    CUE_AMFR; CUE domain found in autocrine motility factor receptor (AMFR) and similar proteins
    cd16455
    Location:339 → 382
    RING-H2_AMFR; RING finger, H2 subclass, found in autocrine motility factor receptor (AMFR) and similar proteins
    pfam18442
    Location:575 → 595
    G2BR; E3 gp78 Ube2g2-binding region (G2BR)

  4. XM_042968526.1 → XP_042824460.1  E3 ubiquitin-protein ligase AMFR isoform X4

    UniProtKB/TrEMBL
    A0A8C9KLG5
    Conserved Domains (3) summary
    COG5243
    Location:86 → 382
    HRD1; HRD ubiquitin ligase complex, ER membrane component [Posttranslational modification, protein turnover, chaperones]
    cd14421
    Location:458 → 498
    CUE_AMFR; CUE domain found in autocrine motility factor receptor (AMFR) and similar proteins
    cd16455
    Location:339 → 382
    RING-H2_AMFR; RING finger, H2 subclass, found in autocrine motility factor receptor (AMFR) and similar proteins
Nucleotide Protein
Heading Accession and Version

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