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ARHGAP5 Rho GTPase activating protein 5 [ Panthera tigris (tiger) ]

Gene ID: 102950155, updated on 10-Mar-2024

Summary

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Gene symbol
ARHGAP5
Gene description
Rho GTPase activating protein 5
See related
Ensembl:ENSPTIG00000011092
Gene type
protein coding
RefSeq status
MODEL
Organism
Panthera tigris
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Feliformia; Felidae; Pantherinae; Panthera
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: B3
Exon count:
9
Annotation release Status Assembly Chr Location
102 current P.tigris_Pti1_mat1.1 (GCF_018350195.1) B3 NC_056665.1 (81374917..81452815)

Chromosome B3 - NC_056665.1Genomic Context describing neighboring genes Neighboring gene NUBP iron-sulfur cluster assembly factor, mitochondrial Neighboring gene cell division cycle-associated protein 3-like Neighboring gene uncharacterized LOC122239250 Neighboring gene U2 spliceosomal RNA Neighboring gene U6 spliceosomal RNA

Genomic regions, transcripts, and products

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Genomic Sequence:
NC_056665.1 Chromosome B3 Reference P.tigris_Pti1_mat1.1 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
rho GTPase-activating protein 5

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Panthera tigris Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference P.tigris_Pti1_mat1.1 Primary Assembly

Genomic

  1. NC_056665.1 Reference P.tigris_Pti1_mat1.1 Primary Assembly

    Range
    81374917..81452815
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_042989532.1 → XP_042845466.1  rho GTPase-activating protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8C9JN94
    Conserved Domains (5) summary
    smart00441
    Location:429 → 481
    FF; Contains two conserved F residues
    cd04373
    Location:1261 → 1445
    RhoGAP_p190; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of p190-like proteins. p190, also named RhoGAP5, plays a role in neuritogenesis and axon branch stability. p190 shows a preference for Rho, over Rac and Cdc42, and consists of an ...
    pfam16512
    Location:260 → 338
    RhoGAP-FF1; p190-A and -B Rho GAPs FF domain
    pfam19518
    Location:556 → 1265
    RhoGAP_pG1_pG2; p190RhoGAP, pG1 and pG2 domains
    cl38936
    Location:31 → 246
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  2. XM_042989530.1 → XP_042845464.1  rho GTPase-activating protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8C9JN94
    Conserved Domains (5) summary
    smart00441
    Location:429 → 481
    FF; Contains two conserved F residues
    cd04373
    Location:1261 → 1445
    RhoGAP_p190; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of p190-like proteins. p190, also named RhoGAP5, plays a role in neuritogenesis and axon branch stability. p190 shows a preference for Rho, over Rac and Cdc42, and consists of an ...
    pfam16512
    Location:260 → 338
    RhoGAP-FF1; p190-A and -B Rho GAPs FF domain
    pfam19518
    Location:556 → 1265
    RhoGAP_pG1_pG2; p190RhoGAP, pG1 and pG2 domains
    cl38936
    Location:31 → 246
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  3. XM_042989534.1 → XP_042845468.1  rho GTPase-activating protein 5 isoform X2

    Conserved Domains (5) summary
    smart00441
    Location:429 → 481
    FF; Contains two conserved F residues
    cd04373
    Location:1260 → 1444
    RhoGAP_p190; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of p190-like proteins. p190, also named RhoGAP5, plays a role in neuritogenesis and axon branch stability. p190 shows a preference for Rho, over Rac and Cdc42, and consists of an ...
    pfam16512
    Location:260 → 338
    RhoGAP-FF1; p190-A and -B Rho GAPs FF domain
    cd22220
    Location:592 → 762
    pseudoGTPaseD_p190RhoGAP-B; pseudoGTPase domain found in p190RhoGAP-B and similar proteins
    cl38936
    Location:31 → 246
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases

  4. XM_042989533.1 → XP_042845467.1  rho GTPase-activating protein 5 isoform X1

    UniProtKB/TrEMBL
    A0A8C9JN94
    Conserved Domains (5) summary
    smart00441
    Location:429 → 481
    FF; Contains two conserved F residues
    cd04373
    Location:1261 → 1445
    RhoGAP_p190; RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of p190-like proteins. p190, also named RhoGAP5, plays a role in neuritogenesis and axon branch stability. p190 shows a preference for Rho, over Rac and Cdc42, and consists of an ...
    pfam16512
    Location:260 → 338
    RhoGAP-FF1; p190-A and -B Rho GAPs FF domain
    pfam19518
    Location:556 → 1265
    RhoGAP_pG1_pG2; p190RhoGAP, pG1 and pG2 domains
    cl38936
    Location:31 → 246
    P-loop_NTPase; P-loop containing Nucleoside Triphosphate Hydrolases
Nucleotide Protein
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