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NF1 neurofibromin 1 [ Chelonia mydas (Green sea turtle) ]

Gene ID: 102941482, updated on 10-Mar-2024

Summary

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Gene symbol
NF1
Gene description
neurofibromin 1
Locus tag
UY3_04972
See related
EnsemblRapid:ENSCMYG00015010164
Gene type
protein coding
RefSeq status
MODEL
Organism
Chelonia mydas
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Archelosauria; Testudinata; Testudines; Cryptodira; Durocryptodira; Americhelydia; Chelonioidea; Cheloniidae; Chelonia
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 17
Exon count:
59
Annotation release Status Assembly Chr Location
103 current rCheMyd1.pri.v2 (GCF_015237465.2) 17 NC_051257.2 (9087817..9255867, complement)
102 previous assembly rCheMyd1.pri (GCF_015237465.1) 17 NC_051257.1 (15947081..16115048)

Chromosome 17 - NC_051257.2Genomic Context describing neighboring genes Neighboring gene uncharacterized LOC122463219 Neighboring gene musashi RNA binding protein 2 Neighboring gene A-kinase anchoring protein 1 Neighboring gene ecotropic viral integration site 2B Neighboring gene oligodendrocyte myelin glycoprotein Neighboring gene uncharacterized LOC122463184 Neighboring gene WD repeat and SOCS box containing 1

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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Related articles in PubMed

  1. Sea turtle fibropapilloma tumors share genomic drivers and therapeutic vulnerabilities with human cancers. Duffy DJ, et al. Commun Biol, 2018. PMID 30271945, Free PMC Article

GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Process Evidence Code Pubs
involved_in regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
neurofibromin

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Chelonia mydas Annotation Release 103 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference rCheMyd1.pri.v2 Primary Assembly

Genomic

  1. NC_051257.2 Reference rCheMyd1.pri.v2 Primary Assembly

    Range
    9087817..9255867 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_037880588.2 → XP_037736516.1  neurofibromin isoform X3

    Conserved Domains (3) summary
    cd05130
    Location:1145 → 1498
    RasGAP_Neurofibromin; Ras-GTPase Activating Domain of neurofibromin
    cd13313
    Location:1675 → 1784
    PH_NF1; Neurofibromin-1 Pleckstrin homology-like domain
    pfam13716
    Location:1549 → 1683
    CRAL_TRIO_2; Divergent CRAL/TRIO domain

  2. XM_037880586.2 → XP_037736514.1  neurofibromin isoform X1

    Related
    ENSCMYP00015015737.1, ENSCMYT00015019100.1
    Conserved Domains (3) summary
    cd05130
    Location:1196 → 1549
    RasGAP_Neurofibromin; Ras-GTPase Activating Domain of neurofibromin
    cd13313
    Location:1726 → 1835
    PH_NF1; Neurofibromin-1 Pleckstrin homology-like domain
    pfam13716
    Location:1600 → 1734
    CRAL_TRIO_2; Divergent CRAL/TRIO domain

  3. XM_037880587.2 → XP_037736515.1  neurofibromin isoform X2

    Related
    ENSCMYP00015015751.1, ENSCMYT00015019115.1
    Conserved Domains (3) summary
    cd05130
    Location:1196 → 1528
    RasGAP_Neurofibromin; Ras-GTPase Activating Domain of neurofibromin
    cd13313
    Location:1705 → 1814
    PH_NF1; Neurofibromin-1 Pleckstrin homology-like domain
    pfam13716
    Location:1579 → 1713
    CRAL_TRIO_2; Divergent CRAL/TRIO domain

  4. XM_043531467.1 → XP_043387402.1  neurofibromin isoform X4

    Related
    ENSCMYP00015015728.1, ENSCMYT00015019089.1
    Conserved Domains (3) summary
    cd05130
    Location:1145 → 1477
    RasGAP_Neurofibromin; Ras-GTPase Activating Domain of neurofibromin
    smart00516
    Location:1509 → 1653
    SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
    cd13313
    Location:1654 → 1763
    PH_NF1; Neurofibromin-1 Pleckstrin homology-like domain

  5. XM_037880589.1 → XP_037736517.1  neurofibromin isoform X5

    Conserved Domains (3) summary
    cd05130
    Location:656 → 1009
    RasGAP_Neurofibromin; Ras-GTPase Activating Domain of neurofibromin
    cd13313
    Location:1186 → 1295
    PH_NF1; Neurofibromin-1 Pleckstrin homology-like domain
    pfam13716
    Location:1060 → 1194
    CRAL_TRIO_2; Divergent CRAL/TRIO domain
Nucleotide Protein
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