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Masp2 MBL associated serine protease 2 [ Peromyscus maniculatus bairdii (prairie deer mouse) ]

Gene ID: 102907907, updated on 10-Mar-2024

Summary

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Gene symbol
Masp2
Gene description
MBL associated serine protease 2
See related
Ensembl:ENSPEMG00000017820
Gene type
protein coding
RefSeq status
MODEL
Organism
Peromyscus maniculatus bairdii (sub-species: bairdii)
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Glires; Rodentia; Myomorpha; Muroidea; Cricetidae; Neotominae; Peromyscus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: 2
Exon count:
13
Annotation release Status Assembly Chr Location
102 current HU_Pman_2.1.3 (GCF_003704035.1) 2 NC_056009.1 (165701426..165714677, complement)
101 previous assembly Pman_1.0 (GCF_000500345.1) Unplaced Scaffold NW_006501092.1 (3406151..3420913, complement)

Chromosome 2 - NC_056009.1Genomic Context describing neighboring genes Neighboring gene chromosome 2 C1orf127 homolog Neighboring gene TAR DNA binding protein Neighboring gene exosome component 10 Neighboring gene mechanistic target of rapamycin kinase Neighboring gene angiopoietin like 7

Genomic regions, transcripts, and products

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Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables calcium ion binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables serine-type endopeptidase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in complement activation, lectin pathway IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in proteolysis IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in extracellular region IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extracellular space IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
mannan-binding lectin serine protease 2
Names
mannan binding lectin serine peptidase 2

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Peromyscus maniculatus bairdii Annotation Release 102 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference HU_Pman_2.1.3 Primary Assembly

Genomic

  1. NC_056009.1 Reference HU_Pman_2.1.3 Primary Assembly

    Range
    165701426..165714677 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006975236.3 → XP_006975298.1  mannan-binding lectin serine protease 2 isoform X1

    UniProtKB/TrEMBL
    A0A6I9L9G6, A0A6J0D4J3
    Related
    ENSPEMP00000019569.1
    Conserved Domains (5) summary
    smart00020
    Location:443 → 677
    Tryp_SPc; Trypsin-like serine protease
    cd00041
    Location:184 → 295
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    cd00190
    Location:444 → 680
    Tryp_SPc; Trypsin-like serine protease; Many of these are synthesized as inactive precursor zymogens that are cleaved during limited proteolysis to generate their active forms. Alignment contains also inactive enzymes that have substitutions of the catalytic triad ...
    pfam00084
    Location:300 → 361
    Sushi; Sushi repeat (SCR repeat)
    pfam14670
    Location:152 → 180
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  2. XM_015994148.2 → XP_015849634.1  mannan-binding lectin serine protease 2 isoform X2

    UniProtKB/TrEMBL
    A0A6J0D394
    Conserved Domains (3) summary
    cd00041
    Location:184 → 295
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam00084
    Location:300 → 361
    Sushi; Sushi repeat (SCR repeat)
    pfam14670
    Location:152 → 180
    FXa_inhibition; Coagulation Factor Xa inhibitory site

  3. XM_042272492.1 → XP_042128426.1  mannan-binding lectin serine protease 2 isoform X3

    Conserved Domains (3) summary
    cd00033
    Location:300 → 335
    CCP; Complement control protein (CCP) modules (aka short consensus repeats SCRs or SUSHI repeats) have been identified in several proteins of the complement system
    smart00179
    Location:138 → 176
    EGF_CA; Calcium-binding EGF-like domain
    cd00041
    Location:184 → 295
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.

  4. XM_006975237.3 → XP_006975299.1  mannan-binding lectin serine protease 2 isoform X4

    UniProtKB/TrEMBL
    A0A6I9L257
    Related
    ENSPEMP00000019571.1
    Conserved Domains (2) summary
    cd00041
    Location:24 → 136
    CUB; CUB domain; extracellular domain; present in proteins mostly known to be involved in development; not found in prokaryotes, plants and yeast.
    pfam14670
    Location:152 → 180
    FXa_inhibition; Coagulation Factor Xa inhibitory site
Nucleotide Protein
Heading Accession and Version

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