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BCR BCR activator of RhoGEF and GTPase [ Elephantulus edwardii (Cape elephant shrew) ]

Gene ID: 102872275, updated on 10-Mar-2024

Summary

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Gene symbol
BCR
Gene description
BCR activator of RhoGEF and GTPase
Gene type
protein coding
RefSeq status
MODEL
Organism
Elephantulus edwardii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Macroscelidea; Macroscelididae; Elephantulus
Orthologs
human mouse all
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Genomic context

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See BCR in Genome Data Viewer
Location:
chromosome: Un
Exon count:
23
Annotation release Status Assembly Chr Location
100 current EleEdw1.0 (GCF_000299155.1) Unplaced Scaffold NW_006400075.1 (1505977..1581272)

NW_006400075.1Genomic Context describing neighboring genes Neighboring gene radial spoke head 14 homolog Neighboring gene G protein subunit alpha z Neighboring gene RAB36, member RAS oncogene family Neighboring gene actin related protein 2/3 complex, subunit 2, 34kDa pseudogene Neighboring gene sperm antigen with calponin homology and coiled-coil domains 1 like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_006400075 unplaced scaffold reference EleEdw1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables GTPase activator activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein serine/threonine kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of GTPase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in protein phosphorylation IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
breakpoint cluster region protein
Names
BCR, RhoGEF and GTPase activating protein

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Elephantulus edwardii Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EleEdw1.0

Genomic

  1. NW_006400075.1 Reference EleEdw1.0

    Range
    1505977..1581272
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006901408.1 → XP_006901470.1  breakpoint cluster region protein

    Conserved Domains (6) summary
    cd08686
    Location:857 → 977
    C2_ABR; C2 domain in the Active BCR (Breakpoint cluster region) Related protein
    cd04387
    Location:996 → 1196
    RhoGAP_Bcr; RhoGAP_Bcr: RhoGAP (GTPase-activator protein [GAP] for Rho-like small GTPases) domain of Bcr (breakpoint cluster region protein)-like proteins. Bcr is a multidomain protein with a variety of enzymatic functions. It contains a RhoGAP and a Rho GEF domain, ...
    pfam00621
    Location:446 → 634
    RhoGEF; RhoGEF domain
    pfam09036
    Location:1 → 53
    Bcr-Abl_Oligo; Bcr-Abl oncoprotein oligomerization domain
    pfam16182
    Location:224 → 377
    AbLIM_anchor; Putative adherens-junction anchoring region of AbLIM
    cl17171
    Location:628 → 821
    PH-like; Pleckstrin homology-like domain
Nucleotide Protein
Heading Accession and Version

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