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PIK3C2B phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta [ Elephantulus edwardii (Cape elephant shrew) ]

Gene ID: 102862958, updated on 10-Mar-2024

Summary

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Gene symbol
PIK3C2B
Gene description
phosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 beta
Gene type
protein coding
RefSeq status
MODEL
Organism
Elephantulus edwardii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Macroscelidea; Macroscelididae; Elephantulus
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
32
Annotation release Status Assembly Chr Location
100 current EleEdw1.0 (GCF_000299155.1) Unplaced Scaffold NW_006399813.1 (2854147..2913615, complement)

NW_006399813.1Genomic Context describing neighboring genes Neighboring gene pleckstrin homology domain containing A6 Neighboring gene protein phosphatase 1 regulatory subunit 15B Neighboring gene MDM4 regulator of p53 Neighboring gene leucine rich repeat neuronal 2

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_006399813 unplaced scaffold reference EleEdw1.0

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 1-phosphatidylinositol-3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables 1-phosphatidylinositol-4-phosphate 3-kinase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphatidylinositol binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in cell migration IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol 3-kinase/protein kinase B signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-3-phosphate biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in phosphatidylinositol-mediated signaling IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
part_of phosphatidylinositol 3-kinase complex IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in plasma membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Elephantulus edwardii Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference EleEdw1.0

Genomic

  1. NW_006399813.1 Reference EleEdw1.0

    Range
    2854147..2913615 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006887899.1 → XP_006887961.1  phosphatidylinositol 4-phosphate 3-kinase C2 domain-containing subunit beta

    Conserved Domains (6) summary
    cd00895
    Location:986 → 1339
    PI3Kc_C2_beta; Catalytic domain of Class II Phosphoinositide 3-kinase beta
    cd07290
    Location:1368 → 1476
    PX_PI3K_C2_beta; The phosphoinositide binding Phox Homology Domain of the Beta Isoform of Class II Phosphoinositide 3-Kinases
    cd04012
    Location:621 → 793
    C2A_PI3K_class_II; C2 domain first repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd08381
    Location:1504 → 1626
    C2B_PI3K_class_II; C2 domain second repeat present in class II phosphatidylinositol 3-kinases (PI3Ks)
    cd00869
    Location:812 → 980
    PI3Ka_II; Phosphoinositide 3-kinase (PI3K) class II, accessory domain (PIK domain); PIK domain is conserved in all PI3 and PI4-kinases. Its role is unclear but it has been suggested to be involved in substrate presentation. In general, class II PI3-kinases ...
    pfam00794
    Location:363 → 465
    PI3K_rbd; PI3-kinase family, ras-binding domain
Nucleotide Protein
Heading Accession and Version

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