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MCF2L MCF.2 cell line derived transforming sequence like [ Chrysochloris asiatica (Cape golden mole) ]

Gene ID: 102833360, updated on 10-Mar-2024

Summary

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Gene symbol
MCF2L
Gene description
MCF.2 cell line derived transforming sequence like
Gene type
protein coding
RefSeq status
MODEL
Organism
Chrysochloris asiatica
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Afrotheria; Chrysochloridae; Chrysochlorinae; Chrysochloris
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
32
Annotation release Status Assembly Chr Location
100 current ChrAsi1.0 (GCF_000296735.1) Unplaced Scaffold NW_006408547.1 (23107541..23409012)

NW_006408547.1Genomic Context describing neighboring genes Neighboring gene tubulin gamma complex component 3 Neighboring gene 60S ribosomal protein L12-like Neighboring gene ATPase phospholipid transporting 11A Neighboring gene ribosomal protein L13 pseudogene Neighboring gene coagulation factor VII Neighboring gene coagulation factor X

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_006408547 unplaced scaffold reference ChrAsi1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables guanyl-nucleotide exchange factor activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables protein binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in intracellular signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
involved_in positive regulation of Rho protein signal transduction IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 
located_in extrinsic component of membrane IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
guanine nucleotide exchange factor DBS

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Chrysochloris asiatica Annotation Release 100 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference ChrAsi1.0 Primary Assembly

Genomic

  1. NW_006408547.1 Reference ChrAsi1.0 Primary Assembly

    Range
    23107541..23409012
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006851546.1 → XP_006851609.1  guanine nucleotide exchange factor DBS

    UniProtKB/TrEMBL
    A0A9B0TEW6
    Conserved Domains (6) summary
    cd11857
    Location:1082 → 1136
    SH3_DBS; Src homology 3 domain of DBL's Big Sister (DBS), a guanine nucleotide exchange factor
    smart00516
    Location:42 → 187
    SEC14; Domain in homologues of a S. cerevisiae phosphatidylinositol transfer protein (Sec14p)
    cd00160
    Location:600 → 777
    RhoGEF; Guanine nucleotide exchange factor for Rho/Rac/Cdc42-like GTPases; Also called Dbl-homologous (DH) domain. It appears that PH domains invariably occur C-terminal to RhoGEF/DH domains.
    cd00176
    Location:321 → 520
    SPEC; Spectrin repeats, found in several proteins involved in cytoskeletal structure; family members include spectrin, alpha-actinin and dystrophin; the spectrin repeat forms a three helix bundle with the second helix interrupted by proline in some sequences; ...
    cd01227
    Location:784 → 915
    PH_Dbs; DBL's big sister protein pleckstrin homology (PH) domain
    pfam00169
    Location:810 → 912
    PH; PH domain
Nucleotide Protein
Heading Accession and Version

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