These reference sequences exist independently of genome builds. Explain
These reference sequences are curated independently of the genome
annotation cycle, so their versions may not match the RefSeq versions in the current
genome build. Identify version mismatches by comparing the version of the RefSeq in this
section to the one reported in Genomic regions, transcripts, and products above.
mRNA and Protein(s)
-
NM_005864.2 → NP_005855.1 embryonal Fyn-associated substrate isoform 1
Status: REVIEWED
- Description
- Transcript Variant: This variant (1) encodes the full length isoform which contains a SH3 domain in the N-terminal region.
- Source sequence(s)
-
AB001466, BE645250
- Consensus CDS
-
CCDS9595.1
- UniProtKB/Swiss-Prot
-
O43281
- Related
- ENSP00000216733, OTTHUMP00000164593, ENST00000216733, OTTHUMT00000071770
- Conserved Domains (2) summary
-
- cd00174
Location:10 – 65
Blast Score: 157
- SH3; Src homology 3 domains; SH3 domains bind to proline-rich ligands with moderate affinity and selectivity, preferentially to PxxP motifs; they play a role in the regulation of enzymes by intramolecular interactions, changing the subcellular localization of ...
- cd11571
Location:431 – 560
Blast Score: 587
- FAT-like_EFS_C; C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein, Embryonal Fyn-associated Substrate; a protein interaction module
-
NM_032459.1 → NP_115835.1 embryonal Fyn-associated substrate isoform 2
Status: REVIEWED
- Description
- Transcript Variant: This variant (2) lacks an internal region of the coding region. The reading frame is maintained, thus a shorter isoform is encoded that lacks the SH3 domain.
- Source sequence(s)
-
AB001467, BE645250
- Consensus CDS
-
CCDS9596.1
- UniProtKB/Swiss-Prot
-
O43281
- Related
- ENSP00000340607, OTTHUMP00000164594, ENST00000351354, OTTHUMT00000071772
- Conserved Domains (1) summary
-
- cd11571
Location:338 – 467
Blast Score: 583
- FAT-like_EFS_C; C-terminal FAT-like Four helix bundle domain, also called DUF3513, of CAS (Crk-Associated Substrate) scaffolding protein, Embryonal Fyn-associated Substrate; a protein interaction module
The following sections contain reference sequences that belong to a
specific genome build. Explain
This section includes genomic Reference
Sequences (RefSeqs) from all assemblies on which this gene is annotated, such as RefSeqs
for chromosomes and scaffolds (contigs) from both reference and alternate assemblies.
Model RNAs and proteins are also reported here.
Reference GRCh37.p5 Primary Assembly
Genomic
-
NC_000014.8 Reference GRCh37.p5 Primary Assembly
- Range
- 23825611..23834842, complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)
Alternate HuRef
Genomic
-
AC_000146.1 Alternate HuRef
- Range
- 3942029..3951261, complement
- Download
- GenBank, FASTA, Sequence Viewer (Graphics)