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FASN fatty acid synthase [ Leptonychotes weddellii (Weddell seal) ]

Gene ID: 102743112, updated on 10-Mar-2024

Summary

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Gene symbol
FASN
Gene description
fatty acid synthase
Gene type
protein coding
RefSeq status
MODEL
Organism
Leptonychotes weddellii
Lineage
Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Laurasiatheria; Carnivora; Caniformia; Pinnipedia; Phocidae; Leptonychotes
Orthologs
human mouse all
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Genomic context

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Location:
chromosome: Un
Exon count:
41
Annotation release Status Assembly Chr Location
101 current LepWed1.0 (GCF_000349705.1) Unplaced Scaffold NW_006384642.1 (492909..509594, complement)

NW_006384642.1Genomic Context describing neighboring genes Neighboring gene G protein pathway suppressor 1 Neighboring gene dihydrouridine synthase 1 like Neighboring gene coiled-coil domain-containing protein 57-like

Genomic regions, transcripts, and products

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Genomic Sequence:
NW_006384642 Unplaced Scaffold Reference LepWed1.0 Primary Assembly

Go to nucleotide: Graphics FASTA GenBank

Bibliography

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GeneRIFs: Gene References Into Functions

General gene information

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Homology

Gene Ontology Provided by RefSeq

Function Evidence Code Pubs
enables 3-oxoacyl-[acyl-carrier-protein] synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables fatty acid synthase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables oxidoreductase activity IEA
Inferred from Electronic Annotation
more info
 PubMed 
enables phosphopantetheine binding IEA
Inferred from Electronic Annotation
more info
 PubMed 
Process Evidence Code Pubs
involved_in fatty acid biosynthetic process IEA
Inferred from Electronic Annotation
more info
 PubMed 
Component Evidence Code Pubs
located_in cytoplasm IEA
Inferred from Electronic Annotation
more info
 PubMed 

General protein information

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Preferred Names
fatty acid synthase

NCBI Reference Sequences (RefSeq)

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RefSeqs of Annotated Genomes: Leptonychotes weddellii Annotation Release 101 details...Open this link in a new tab

The following sections contain reference sequences that belong to a specific genome build. Explain

Reference LepWed1.0 Primary Assembly

Genomic

  1. NW_006384642.1 Reference LepWed1.0 Primary Assembly

    Range
    492909..509594 complement
    Download
    GenBank, FASTA, Sequence Viewer (Graphics)

mRNA and Protein(s)

  1. XM_006743100.2 → XP_006743163.1  fatty acid synthase

    UniProtKB/TrEMBL
    A0A2U3YHU6
    Conserved Domains (9) summary
    cd08954
    Location:1878 → 2118
    KR_1_FAS_SDR_x; beta-ketoacyl reductase (KR) domain of fatty acid synthase (FAS), subgroup 1, complex (x) SDRs
    smart00829
    Location:1570 → 1860
    PKS_ER; Enoylreductase
    PRK10252
    Location:2133 → 2331
    entF; enterobactin non-ribosomal peptide synthetase EntF
    cd00833
    Location:2 → 404
    PKS; polyketide synthases (PKSs) polymerize simple fatty acids into a large variety of different products, called polyketides, by successive decarboxylating Claisen condensations. PKSs can be divided into 2 groups, modular type I PKSs consisting of one or ...
    pfam00698
    Location:496 → 812
    Acyl_transf_1; Acyl transferase domain
    pfam08242
    Location:1248 → 1346
    Methyltransf_12; Methyltransferase domain
    pfam16197
    Location:362 → 472
    KAsynt_C_assoc; Ketoacyl-synthetase C-terminal extension
    cl00509
    Location:878 → 1113
    hot_dog; The hotdog fold was initially identified in the E. coli FabA (beta-hydroxydecanoyl-acyl carrier protein (ACP)-dehydratase) structure and subsequently in 4HBT (4-hydroxybenzoyl-CoA thioesterase) from Pseudomonas. A number of other seemingly unrelated ...
    cl21494
    Location:2249 → 2509
    Abhydrolase; alpha/beta hydrolases
Nucleotide Protein
Heading Accession and Version

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